Area of research
Molecular Biology · Surgery
Research interest
Research focused on Induced pluripotent stem cell and Transcriptome, with related work in Embryonic stem cell, Stem cell, Neurotoxicity. Notable publications include 'Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach', 'In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities', and 'Human brain organoids assemble functionally integrated bilateral optic vesicles'.
Modulating Collagen I Expression in Fibroblasts by CRISPR-Cas9 Base Editing of the Collagen 1A1 Promoter
Correction to: Toxicogenomics directory of chemically exposed human hepatocytes
Human brain organoids assemble functionally integrated bilateral optic vesicles
Following the adverse outcome pathway from micronucleus to cancer using H2B-eGFP transgenic healthy stem cells
Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience
In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities
Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests
Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells
“Watching the Detectives” report of the general assembly of the EU project DETECTIVE Brussels, 24–25 November 2015
Toxicogenomics directory of chemically exposed human hepatocytes
DETECTIVE: detection of endpoints and biomarkers for repeated dose toxicity testing using in vitro systems. Towards the replacement of in vivo repeated dose systemic toxicity testing.
VUBIR (Vrije Universiteit Brussel) 2014cited by 0position: last
DETECTIVE: detection of endpoints and biomarkers for repeated dose toxicity testing using in vitro systems.
VUBIR (Vrije Universiteit Brussel) 2014cited by 0position: last
Reconsidering pluripotency tests: Do we still need teratoma assays?
The Disease-Specific Phenotype in Cardiomyocytes Derived from Induced Pluripotent Stem Cells of Two Long QT Syndrome Type 3 Patients
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach
Induced Pluripotent Mesenchymal Stromal Cell Clones Retain Donor-derived Differences in DNA Methylation Profiles