Area of research
Molecular Biology · Oncology
Research interest
Research focused on Transcriptome and Loss of heterozygosity, with related work in Acute kidney injury, Fecal bacteriotherapy, Endoneurium. Notable publications include 'Germline loss-of-function mutations in LZTR1 predispose to an inherited disorder of multiple schwannomas', 'β- d - N 4 -Hydroxycytidine Is a Potent Anti-alphavirus Compound That Induces a High Level of Mutations in the Viral Genome', and 'Single-Cell RNA Sequencing Identifies Candidate Renal Resident Macrophage Gene Expression Signatures across Species'.
Identifying differentiation markers between dermal fibroblasts and adipose-derived mesenchymal stromal cells (AD-MSCs) in human visceral and subcutaneous tissues using single-cell transcriptomics
ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression
Cx3cr1 controls kidney resident macrophage heterogeneity
Natural and Recombinant SARS-CoV-2 Isolates Rapidly Evolve <i>In Vitro</i> to Higher Infectivity through More Efficient Binding to Heparan Sulfate and Reduced S1/S2 Cleavage
Human gut microbial communities dictate efficacy of anti-PD-1 therapy in a humanized microbiome mouse model of glioma
Therapeutic Effects of Dietary Soybean Genistein on Triple-Negative Breast Cancer via Regulation of Epigenetic Mechanisms
Targeting the HuR Oncogenic Role with a New Class of Cytoplasmic Dimerization Inhibitors
Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells
An individualized mosaic of maternal microbial strains is transmitted to the infant gut microbial community
Therapeutically actionable PAK4 is amplified, overexpressed, and involved in bladder cancer progression
The impact of <i>Lactococcus lactis</i> (probiotic nasal rinse) co‐culture on growth of patient‐derived strains of <i>Pseudomonas aeruginosa</i>
Single-Cell RNA Sequencing Identifies Candidate Renal Resident Macrophage Gene Expression Signatures across Species
Resident macrophages reprogram toward a developmental state after acute kidney injury
Tissue-Resident Macrophages Promote Renal Cystic Disease
The Purple Sea Urchin Strongylocentrotus purpuratus Demonstrates a Compartmentalization of Gut Bacterial Microbiota, Predictive Functional Attributes, and Taxonomic Co-Occurrence
Podocyte-specific expression of Cre recombinase promotes glomerular basement membrane thickening
CYP3A5 genotype affects time to therapeutic tacrolimus level in pediatric kidney transplant recipients
Immunophenotyping and transcriptional profiling of in vitro cultured human adipose tissue derived stem cells
Metagenomic Analysis of Microbial Community Compositions and Cold-Responsive Stress Genes in Selected Antarctic Lacustrine and Soil Ecosystems
β- <scp>d</scp> - <i>N</i> <sup>4</sup> -Hydroxycytidine Is a Potent Anti-alphavirus Compound That Induces a High Level of Mutations in the Viral Genome
Identification of donor microbe species that colonize and persist long term in the recipient after fecal transplant for recurrent Clostridium difficile
The Human Blood-Nerve Barrier Transcriptome
Kinase analysis of penile squamous cell carcinoma on multiple platforms to identify potential therapeutic targets
The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis
Somatic Mutations Modulate Autoantibodies against Galactose-Deficient IgA1 in IgA Nephropathy
Reprogramming by De-bookmarking the Somatic Transcriptional Program through Targeting of BET Bromodomains
Colonization potential to reconstitute a microbe community in patients detected early after fecal microbe transplant for recurrent C. difficile
Identification of new regulators of embryonic patterning and morphogenesis in Xenopus gastrulae by RNA sequencing
Draft Genome Sequence of <i>Janthinobacterium</i> sp. Ant5-2-1, Isolated from Proglacial Lake Podprudnoye in the Schirmacher Oasis of East Antarctica
Allelic series of Huntington's disease knock-in mice reveals expression discorrelates