Area of research
Public Health, Environmental and Occupational Health · Molecular Biology
Research interest
Research focused on Cancer research and Ubiquitin ligase, with related work in Prostate cancer, Ubiquitin, DNA methylation. Notable publications include 'Prostate Cancer-associated SPOP mutations enhance cancer cell survival and docetaxel resistance by upregulating Caprin1-dependent stress granule assembly', 'SPOP mutation induces DNA methylation via stabilizing GLP/G9a', and 'SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression'.
Exploring the therapeutic potential of natural compounds for Alzheimer's disease: Mechanisms of action and pharmacological properties
Multifunctional Gomisin B enhances cognitive function in APP/PS1 transgenic mice by regulating Aβ clearance and neuronal apoptosis
SPOP mutations promote tumor immune escape in endometrial cancer via the IRF1–PD-L1 axis
A nomogram for predicting prognosis of multiple myeloma patients based on a ubiquitin-proteasome gene signature
Development and Internal Validation of a Model Predicting the Risk of Recurrent Stroke for Middle-Aged and Elderly Patients: A Retrospective Cohort Study
SPOP mutation induces DNA methylation via stabilizing GLP/G9a
SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition
Prostate Cancer-associated SPOP mutations enhance cancer cell survival and docetaxel resistance by upregulating Caprin1-dependent stress granule assembly
CRL3–SPOP ubiquitin ligase complex suppresses the growth of diffuse large B-cell lymphoma by negatively regulating the MyD88/NF-κB signaling
SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression
ARRDC1 and ARRDC3 act as tumor suppressors in renal cell carcinoma by facilitating YAP1 degradation.
PubMed 2018cited by 52position: middle