Maureen E. Balestra — Gladstone Institutes

Area of research

Physiology · Molecular Biology

Research interest

Research focused on Induced pluripotent stem cell and Reprogramming, with related work in Apolipoprotein E, Tauopathy, Repurposing. Notable publications include 'Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor', 'Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector', and 'Genetic Correction of Tauopathy Phenotypes in Neurons Derived from Human Induced Pluripotent Stem Cells'.

Recent publications

Experimental and real-world evidence supporting the computational repurposing of bumetanide for APOE4-related Alzheimer’s disease

Nature Aging 2021cited by 109position: middledoi

Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector

Nature Medicine 2018cited by 441position: middledoi

Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia

Acta Neuropathologica 2018cited by 40position: middledoi

Genetic Correction of Tauopathy Phenotypes in Neurons Derived from Human Induced Pluripotent Stem Cells

Stem Cell Reports 2013cited by 127position: middledoi

Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor

Cell stem cell 2012cited by 532position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Yadong Huang · Gladstone Institutes4 papers (2012–2018)Bruce L. Miller · University at Buffalo, State University of New York3 papers (2013–2018)David Walker · Gladstone Institutes3 papers (2012–2018)Karen Ring · Buck Institute for Research on Aging2 papers (2012–2013)William W. Seeley · Hammersmith Hospital2 papers (2013–2018)Chengzhong Wang · Yancheng Second People's Hospital2 papers (2013–2018)Gang Li · Advantest (Singapore)2 papers (2012–2018)Anna Karydas · University of California, San Francisco2 papers (2013–2018)Leslie M. Tong · Nurix (United States)2 papers (2012–2013)Helen Fong · Rapt Therapeutics (United States)1 papers (2013–2013)William R. Zhang · New York Medical College1 papers (2012–2012)Lea T. Grinberg · Mayo Clinic in Arizona1 papers (2018–2018)Nadia Storm · National Health Laboratory Service1 papers (2018–2018)Alissa L. Nana · University of California, San Francisco1 papers (2018–2018)R Myers · Flatiron Health (United States)1 papers (2018–2018)Kenneth S. Kosik · University of Houston1 papers (2013–2013)Adam L. Boxer · Brunel University of London1 papers (2013–2013)Salvatore Spina · University Memory and Aging Center1 papers (2018–2018)Robyn Javier · Gladstone Institutes1 papers (2012–2012)Seo Yeon Yoon · Gladstone Institutes1 papers (2018–2018)

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