Area of research
Public Health, Environmental and Occupational Health · Hematology
Research interest
Research interests include Down syndrome and intellectual disability research, Acute Myeloid Leukemia Research, Acute Lymphoblastic Leukemia research, and Alzheimer's disease research and treatments.
Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels
Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain
Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome
Brief Report: Isogenic Induced Pluripotent Stem Cell Lines From an Adult With Mosaic Down Syndrome Model Accelerated Neuronal Ageing and Neurodegeneration
Frequent cases of RAS-mutated Down syndrome acute lymphoblastic leukaemia lack JAK2 mutations
Exome sequencing identifies putative drivers of progression of transient myeloproliferative disorder to AMKL in infants with Down syndrome