Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genetic Associations and Epidemiology, Epigenetics and DNA Methylation, Telomeres, Telomerase, and Senescence, and Cancer Genomics and Diagnostics.
Translational genomics of osteoarthritis in 1,962,069 individuals
A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies
Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood
Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele
Nitazoxanide and tizoxanide demonstrate high levels of <i>in vitro</i> activity against metronidazole-susceptible and metronidazole-resistant <i>Trichomonas vaginalis</i> clinical isolates
<i>Chlamydia trachomatis</i>-specific interferon-γ-producing CD8 T-cells are associated with lower chlamydia bacterial load in reinfected women
Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations
Novel functional insights into ischemic stroke biology provided by the first genome-wide association study of stroke in indigenous Africans
Utility of a Systolic Blood Pressure Polygenic Risk Score With Chlorthalidone Response
A methylation risk score for chronic kidney disease: a HyperGEN study
Polygenic Risk for Type 2 Diabetes in African Americans
Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes
Stroke occurrence by hypertension treatment status in Ghana and Nigeria: A case-control study
Pharmacogenomics of coronary artery response to intravenous gamma globulin in kawasaki disease
Returning integrated genomic risk and clinical recommendations: The eMERGE study
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis
Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease
Patient-level and system-level determinants of stroke fatality across 16 large hospitals in Ghana and Nigeria: a prospective cohort study
Epigenetic age acceleration correlates with BMI in young adults
The Pace of Biological Aging Predicts Nonspecific Chronic Low Back Pain Severity
The pace of biological aging helps explain the association between insomnia and chronic low back pain
Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study
The genetic determinants of recurrent somatic mutations in 43,693 blood genomes
Identification of Trichomonas vaginalis 5-Nitroimidazole Resistance Targets
Metabolite profiles and DNA methylation in metabolic syndrome: a two-sample, bidirectional Mendelian randomization
Genome-wide DNA methylation analysis implicates enrichment of interferon pathway in African American patients with Systemic Lupus Erythematosus and European Americans with lupus nephritis
Risk factors affecting polygenic score performance across diverse cohorts
Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations
Genome-wide polygenic score to predict chronic kidney disease across ancestries
Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential