Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genetic Associations and Epidemiology, Epigenetics and DNA Methylation, Metabolomics and Mass Spectrometry Studies, and Blood Pressure and Hypertension Studies.
Association Between Cigarette Smoking and Subclinical Markers of Cardiovascular Harm
A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies
Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood
Novel risk loci encompassing genes influencing STAT3, GPCR, and oxidative stress signaling are associated with co-morbid GERD and COPD
Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations
Sex‐Associated Metabolites and Incident Stroke, Incident Coronary Heart Disease, Hypertension, and Chronic Kidney Disease in the REGARDS Cohort
Utility of a Systolic Blood Pressure Polygenic Risk Score With Chlorthalidone Response
Endothelial Dysfunction Biomarkers and CKD Incidence in the REGARDS Cohort
A methylation risk score for chronic kidney disease: a HyperGEN study
Polygenic Risk for Type 2 Diabetes in African Americans
Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes
Returning integrated genomic risk and clinical recommendations: The eMERGE study
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis
Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease
Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing
The predominant PAR4 variant in individuals of African ancestry worsens murine and human stroke outcomes
Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas
Association of Circulating Metabolites With Racial Disparities in Hypertension and Stroke in the REGARDS Study
Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study
Investigating Gene–Diet Interactions Impacting the Association Between Macronutrient Intake and Glycemic Traits
The genetic determinants of recurrent somatic mutations in 43,693 blood genomes
Trimethylamine N-Oxide and White Matter Hyperintensity Volume Among Patients With Acute Ischemic Stroke
Metabolite profiles and DNA methylation in metabolic syndrome: a two-sample, bidirectional Mendelian randomization
Genetic diversity fuels gene discovery for tobacco and alcohol use
Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations
Genome-wide polygenic score to predict chronic kidney disease across ancestries
Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential
Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed
Whole genome sequence analysis of blood lipid levels in >66,000 individuals
Race-Dependent Association of High-Density Lipoprotein Cholesterol Levels With Incident Coronary Artery Disease