Area of research
Immunology · Rheumatology
Research interest
Research interests include Biology, CD8, T-cell receptor, Major histocompatibility complex, T cell, and Antigen.
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity
Targeted suppression of autoreactive CD8+ T-cell activation using blocking anti-CD8 antibodies
Naive CD8<sup>+</sup> T‐cell precursors display structured TCR repertoires and composite antigen‐driven selection dynamics
Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes
Peptide length determines the outcome of TCR/peptide-MHCI engagement
Human β-Cell Killing by Autoreactive Preproinsulin-Specific CD8 T Cells Is Predominantly Granule-Mediated With the Potency Dependent Upon T-Cell Receptor Avidity