Area of research
Immunology · Radiology, Nuclear Medicine and Imaging
Research interest
Research interests include Immune Cell Function and Interaction, T-cell and B-cell Immunology, Immunotherapy and Immune Responses, and Monoclonal and Polyclonal Antibodies Research.
Cancer immunotherapy by γδ T cells
Diverse cytomegalovirus US11 antagonism and MHC-A evasion strategies reveal a tit-for-tat coevolutionary arms race in hominids
CD4+ T cell-mediated recognition of a conserved cholesterol-dependent cytolysin epitope generates broad antibacterial immunity
Atypical sideways recognition of CD1a by autoreactive γδ T cell receptors
A multilayered immune system through the lens of unconventional T cells
Canonical T cell receptor docking on peptide–MHC is essential for T cell signaling
Repeated <i>Plasmodium falciparum</i> infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire
CD1a selectively captures endogenous cellular lipids that broadly block T cell response
Human skin is colonized by T cells that recognize CD1a independently of lipid
Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1
Human γδ T cells recognize CD1b by two distinct mechanisms
Virus-Mediated Suppression of the Antigen Presentation Molecule MR1
<i>Nfkb2</i> variants reveal a p100-degradation threshold that defines autoimmune susceptibility
Peripheral Blood Mucosal-Associated Invariant T Cells in Tuberculosis Patients and Healthy Mycobacterium tuberculosis-Exposed Controls
Human CD8+ T cell cross-reactivity across influenza A, B and C viruses
Chronic Inflammation Permanently Reshapes Tissue-Resident Immunity in Celiac Disease
A comprehensive review and performance evaluation of bioinformatics tools for HLA class I peptide-binding prediction
IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection
HLA variation and disease
T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids
HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome
A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids
A molecular basis of human T cell receptor autoreactivity toward self-phospholipids
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity
T cell receptor recognition of CD1b presenting a mycobacterial glycolipid
Targeted suppression of autoreactive CD8+ T-cell activation using blocking anti-CD8 antibodies
HIV-1–Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection
The burgeoning family of unconventional T cells
Impairment of immunity to <i>Candida</i> and <i>Mycobacterium</i> in humans with bi-allelic <i>RORC</i> mutations
Lipid and small-molecule display by CD1 and MR1