Area of research
Immunology · Pathology and Forensic Medicine
Research interest
Research interests include Biology, Immunology, Cell biology, Psoriasis, Experimental autoimmune encephalomyelitis, and Medicine.
IL-17 Signaling in Keratinocytes Orchestrates the Defense against Staphylococcus aureus Skin Infection
Skin Sodium Accumulates in Psoriasis and Reflects Disease Severity
Posttranslational modifications by ADAM10 shape myeloid antigen-presenting cell homeostasis in the splenic marginal zone
Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood–brain barrier
Laquinimod dampens IL-1β signaling and Th17-polarizing capacity of monocytes in patients with MS
Imiquimod-Induced Psoriasis in Mice Depends on the IL-17 Signaling of Keratinocytes
Lugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors
Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology
IL-17+ CD8+ T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis
Keratinocyte-derived IκBζ drives psoriasis and associated systemic inflammation
Dimethyl fumarate alters intracellular Ca2+ handling in immune cells by redox-mediated pleiotropic effects
Regulation of IL-22BP in psoriasis
Alternative Splice Forms of CYLD Mediate Ubiquitination of SMAD7 to Prevent TGFB Signaling and Promote Colitis
EBI2 in splenic and local immune responses and in autoimmunity
Expression of IL-17F is associated with non-pathogenic Th17 cells
NF-κB inducing kinase (NIK) is an essential post-transcriptional regulator of T-cell activation affecting F-actin dynamics and TCR signaling
EBI2 – Sensor for dihydroxycholesterol gradients in neuroinflammation
The actin remodeling protein cofilin is crucial for thymic αβ but not γδ T-cell development
EBI2 Is Highly Expressed in Multiple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4 T Cells
TGF-β inhibitor Smad7 regulates dendritic cell-induced autoimmunity
Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation
IL‐1 signaling is critical for expansion but not generation of autoreactive GM‐CSF+ Th17 cells
T cell mediated pathogenesis in EAE: Molecular mechanisms
Improved method to retain cytosolic reporter protein fluorescence while staining for nuclear proteins
Inflammatory demyelination induces glia alterations and ganglion cell loss in the retina of an experimental autoimmune encephalomyelitis model
IL-6 Regulates Neutrophil Microabscess Formation in IL-17A-Driven Psoriasiform Lesions
Subclinical CNS Inflammation as Response to a Myelin Antigen in Humanized Mice
Dendritic Cells Ameliorate Autoimmunity in the CNS by Controlling the Homeostasis of PD-1 Receptor+ Regulatory T Cells
An Alternative Pathway of Imiquimod-Induced Psoriasis-Like Skin Inflammation in the Absence of Interleukin-17 Receptor A Signaling