Area of research
Molecular Biology · Hematology
Research interest
Research interests include Cancer-related gene regulation, Acute Myeloid Leukemia Research, Epigenetics and DNA Methylation, and Protein Degradation and Inhibitors.
Structural insights into the regulation of monomeric and dimeric apelin receptor
The SWI/SNF chromatin-remodeling subunit DPF2 facilitates NRF2-dependent antiinflammatory and antioxidant gene expression
Epigenetic and Transcriptional Regulation of Innate Immunity in Cancer
RAC1 plays an essential role in estrogen receptor alpha function in breast cancer cells
p300 suppresses the transition of myelodysplastic syndromes to acute myeloid leukemia
PRMT5-mediated histone arginine methylation antagonizes transcriptional repression by polycomb complex PRC2
TAF1 plays a critical role in AML1-ETO driven leukemogenesis
PRMT5 Regulates DNA Repair by Controlling the Alternative Splicing of Histone-Modifying Enzymes
CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis
Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis
Caspase-3 controls AML1-ETO–driven leukemogenesis via autophagy modulation in a ULK1-dependent manner
Loss of Asxl2 leads to myeloid malignancies in mice
Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity
Loss of p300 accelerates MDS-associated leukemogenesis
Arginine methyltransferase PRMT5 is essential for sustaining normal adult hematopoiesis
The Role of Histone Acetyltransferases in Normal and Malignant Hematopoiesis
Regulation of AKT signaling by Id1 controls t(8;21) leukemia initiation and progression