Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Angiogenesis and VEGF in Cancer, Histone Deacetylase Inhibitors Research, Protease and Inhibitor Mechanisms, and Cancer-related gene regulation.
The SWI/SNF chromatin-remodeling subunit DPF2 facilitates NRF2-dependent antiinflammatory and antioxidant gene expression
Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia
p300 suppresses the transition of myelodysplastic syndromes to acute myeloid leukemia
PRMT5-mediated histone arginine methylation antagonizes transcriptional repression by polycomb complex PRC2
Estrogen induces dynamic ERα and RING1B recruitment to control gene and enhancer activities in luminal breast cancer
TAF1 plays a critical role in AML1-ETO driven leukemogenesis
PRMT5 Regulates DNA Repair by Controlling the Alternative Splicing of Histone-Modifying Enzymes
CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis
Caspase-3 controls AML1-ETO–driven leukemogenesis via autophagy modulation in a ULK1-dependent manner
Overcoming evasive resistance from vascular endothelial growth factor a inhibition in sarcomas by genetic or pharmacologic targeting of hypoxia‐inducible factor 1α