Area of research
Genetics · Molecular Biology
Research interest
Research interests include LYN, Chronic lymphocytic leukemia, Cell biology, Leukemia, Protein tyrosine phosphatase, and Autophagy.
A novel class of selective CK2 inhibitors targeting its open hinge conformation
Targeted activation of the SHP-1/PP2A signaling axis elicits apoptosis of chronic lymphocytic leukemia cells
A new molecular link between defective autophagy and erythroid abnormalities in chorea-acanthocytosis
Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A
Cortactin, another player in the Lyn signaling pathway, is over-expressed and alternatively spliced in leukemic cells from patients with B-cell chronic lymphocytic leukemia
Lyn-mediated procaspase 8 dimerization blocks apoptotic signaling in B-cell chronic lymphocytic leukemia
The tyrosine phosphatase SHP-1 inhibits proliferation of activated hepatic stellate cells by impairing PDGF receptor signaling