Area of research
Genetics · Hepatology
Research interest
Research interests include LYN, Chronic lymphocytic leukemia, Cell biology, Phosphorylation, Cancer research, and Chemistry.
Neural stem/progenitor cells from olfactory neuroepithelium collected by nasal brushing as a cell model reflecting molecular and cellular dysfunctions in schizophrenia
The mitochondrial chaperone TRAP1 regulates F-ATP synthase channel formation
Aerobic pyruvate metabolism sensitizes cells to ferroptosis primed by GSH depletion
Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis
Fyn specifically Regulates the activity of red cell glucose-6-phosphate-dehydrogenase
In Chronic Lymphocytic Leukemia the JAK2/STAT3 Pathway Is Constitutively Activated and Its Inhibition Leads to CLL Cell Death Unaffected by the Protective Bone Marrow Microenvironment
Mitochondrial apoptosis is induced by Alkoxy phenyl-1-propanone derivatives through PP2A-mediated dephosphorylation of Bad and Foxo3A in CLL
Absence of Neurofibromin Induces an Oncogenic Metabolic Switch via Mitochondrial ERK-Mediated Phosphorylation of the Chaperone TRAP1
Targeted activation of the SHP-1/PP2A signaling axis elicits apoptosis of chronic lymphocytic leukemia cells
A new molecular link between defective autophagy and erythroid abnormalities in chorea-acanthocytosis
Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A
Astaxanthin Improves Human Sperm Capacitation by Inducing Lyn Displacement and Activation
Cortactin, another player in the Lyn signaling pathway, is over-expressed and alternatively spliced in leukemic cells from patients with B-cell chronic lymphocytic leukemia
MBNL142 and MBNL143 gene isoforms, overexpressed in DM1-patient muscle, encode for nuclear proteins interacting with Src family kinases
Lyn-mediated procaspase 8 dimerization blocks apoptotic signaling in B-cell chronic lymphocytic leukemia
The tyrosine phosphatase SHP-1 inhibits proliferation of activated hepatic stellate cells by impairing PDGF receptor signaling
Inhibition of Protein Kinase CK2 by Flavonoids and Tyrphostins. A Structural Insight
Membrane association of peroxiredoxin-2 in red cells is mediated by the N-terminal cytoplasmic domain of band 3
HS1, a Lyn Kinase Substrate, Is Abnormally Expressed in B-Chronic Lymphocytic Leukemia and Correlates with Response to Fludarabine-Based Regimen