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Giuseppe Zagotto

University of Padua · IT
Area of research
Molecular Biology · Toxicology
Research interest
Research interests include Chemistry, Pharmacology, Medicine, In silico, Oxidative stress, and Biochemistry.
h-index
citations
986
works
28
NIH funding
primary concept
email

Recent publications

ROS-Scavenging Selenofluoxetine Derivatives Inhibit <i>In Vivo</i> Serotonin Reuptake
ACS Omega 2022cited by 28position: middledoi
Therapeutic Potential of Phosphodiesterase Inhibitors against Neurodegeneration: The Perspective of the Medicinal Chemist
ACS Chemical Neuroscience 2020cited by 52position: middledoi
Antioxidant Potential of Psychotropic Drugs: From Clinical Evidence to In Vitro and In Vivo Assessment and toward a New Challenge for in Silico Molecular Design
Antioxidants 2020cited by 47position: middledoi
Plant natural products with anti-thyroid cancer activity
Fitoterapia 2020cited by 28position: middledoi
A computational approach to drug repurposing against SARS-CoV-2 RNA dependent RNA polymerase (RdRp)
Journal of Biomolecular Structure and Dynamics 2020cited by 28position: middledoi
A novel class of selective CK2 inhibitors targeting its open hinge conformation
European Journal of Medicinal Chemistry 2020cited by 26position: middledoi
Pharmacophore-guided discovery of CDC25 inhibitors causing cell cycle arrest and tumor regression
Scientific Reports 2019cited by 43position: middledoi
Semi-synthetic isoflavones as BACE-1 inhibitors against Alzheimer’s disease
Bioorganic Chemistry 2019cited by 34position: middledoi
Major Depressive Disorder and Oxidative Stress: In Silico Investigation of Fluoxetine Activity against ROS
Applied Sciences 2019cited by 32position: middledoi
Effects of point mutations in the binding pocket of the mouse major urinary protein MUP20 on ligand affinity and specificity
Scientific Reports 2019cited by 27position: middledoi
Natural phosphodiesterase 5 (PDE5) inhibitors: a computational approach
Natural Product Research 2019cited by 25position: middledoi
Biological effects and potential mechanisms of action of Pistacia lentiscus Chios mastic extract in Caco-2 cell model
Journal of Functional Foods 2019cited by 23position: middledoi
Synthesis and biological evaluation of heteroalicyclic cyanoguanidines at histamine receptors
Archiv der Pharmazie 2019cited by 5position: middledoi
Mitochondrial apoptosis is induced by Alkoxy phenyl-1-propanone derivatives through PP2A-mediated dephosphorylation of Bad and Foxo3A in CLL
Leukemia 2018cited by 34position: middledoi
The Medicinal Chemistry of Natural and Semisynthetic Compounds against Parkinson’s and Huntington’s Diseases
ACS Chemical Neuroscience 2017cited by 39position: middledoi
An Overview of New Possible Treatments of Alzheimer's Disease, Based on Natural Products and Semi-Synthetic Compounds
Current Medicinal Chemistry 2017cited by 38position: middledoi
Targeted activation of the SHP-1/PP2A signaling axis elicits apoptosis of chronic lymphocytic leukemia cells
Haematologica 2017cited by 29position: middledoi
Preliminary studies of berberine and its semi-synthetic derivatives as a promising class of multi-target anti-parkinson agents
Natural Product Research 2017cited by 29position: lastdoi
Mechanistic Insight into the Oxidation of Organic Phenylselenides by H<sub>2</sub>O<sub>2</sub>
Chemistry - A European Journal 2016cited by 67position: middledoi
New Therapeutic Applications of Phosphodiesterase 5 Inhibitors (PDE5-Is)
Current Medicinal Chemistry 2016cited by 37position: lastdoi
Vanillin Analogues o-Vanillin and 2,4,6-Trihydroxybenzaldehyde Inhibit NFĸB Activation and Suppress Growth of A375 Human Melanoma
Anticancer Research 2016cited by 31position: middledoi
Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A
Blood 2015cited by 46position: middledoi
Design, validation and efficacy of bisubstrate inhibitors specifically affecting ecto-CK2 kinase activity
Biochemical Journal 2015cited by 30position: middledoi
New naphthoquinone derivatives against glioma cells
European Journal of Medicinal Chemistry 2015cited by 27position: lastdoi
Identification and Characterization of New DNA G-Quadruplex Binders Selected by a Combination of Ligand and Structure-Based Virtual Screening Approaches
Journal of Medicinal Chemistry 2013cited by 86position: middledoi
Iodine status in schoolchildren living in northeast italy:the importance of iodized-salt use and milk consumption
European Journal of Clinical Nutrition 2013cited by 36position: middledoi
Exploiting the repertoire of CK2 inhibitors to target DYRK and PIM kinases
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 2013cited by 28position: middledoi
Ellagic Acid and Polyhydroxylated Urolithins Are Potent Catalytic Inhibitors of Human Topoisomerase II: An in Vitro Study
Journal of Agricultural and Food Chemistry 2012cited by 31position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Giovanni Ribaudo · University of Padua22 papers (2015–2022)Enrico Zanforlin · University of Padua5 papers (2017–2020)Alberto Ongaro · University of Padua5 papers (2019–2020)Laura Orian · University of Padua4 papers (2016–2022)Susi Barollo · University of Padua4 papers (2013–2020)Raffaele Pezzani · University of Padua4 papers (2015–2020)Mario A. Pagano · University of Padua4 papers (2015–2018)Valentina Trimarco · University of Padua3 papers (2015–2018)Stefania Sarno · University of Padua3 papers (2013–2020)Francesca Zonta · University of Padua3 papers (2015–2020)Livio Trentin · Veneto Institute of Molecular Medicine3 papers (2015–2018)Anna Maria Brunati · University of Padua3 papers (2015–2018)Federica Frezzato · University of Padua3 papers (2015–2018)Marco Redaelli · University of Padua3 papers (2013–2019)Monica Facco · Consorci Institut D'Investigacions Biomediques August Pi I Sunyer3 papers (2015–2018)Elena Tibaldi · University of Padua3 papers (2015–2018)Lorenzo A. Pinna · University of Padua3 papers (2013–2019)Valeria Pavan · University of Padua3 papers (2015–2017)Marco Bortoli · University of Padua3 papers (2016–2022)Maria Ruzzene · University of Padua3 papers (2013–2020)