Area of research
Physiology · Molecular Biology
Research interest
Research interests include Biology, Neurodegeneration, Epigenomics, Neuroscience, Chromatin, and Histone.
A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation
HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer’s disease
S-nitrosylation of E3 ubiquitin-protein ligase RNF213 alters non-canonical Wnt/Ca+2 signaling in the P301S mouse model of tauopathy
APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types
Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer’s human brains
The Transcription Factor Sp3 Cooperates with HDAC2 to Regulate Synaptic Function and Plasticity in Neurons
Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior
Integrative analysis of 111 reference human epigenomes
Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes
Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer’s disease