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Tak Ko

McGovern Institute for Brain Research · US
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Area of research
Molecular Biology · Spectroscopy
Research interest
Research interests include Advanced Proteomics Techniques and Applications, Alzheimer's disease research and treatments, Genomics and Chromatin Dynamics, and Pluripotent Stem Cells Research.
h-index
14
citations
3,374
works
24
NIH funding
primary concept
Biology
email

Recent publications

Comprehensive Proteomics Metadata and Integrative Web Portals Facilitate Sharing and Integration of LINCS Multiomics Data
Molecular & Cellular Proteomics 2025cited by 1position: middledoi
Author Correction: APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes
Nature 2024cited by 7position: middledoi
APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes
Nature 2022cited by 486position: middledoi
Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors
Cell stem cell 2022cited by 98position: middledoi
Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes
Nature Medicine 2020cited by 293position: middledoi
APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types
Neuron 2018cited by 1,140position: middledoi
A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations
Cell Systems 2018cited by 94position: middledoi
Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia
Journal of Neuroscience 2017cited by 163position: middledoi
Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer’s Disease Phenotypes
PLoS ONE 2016cited by 573position: middledoi
Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior
Nature Neuroscience 2016cited by 106position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Li‐Huei Tsai · Broad Institute6 papers (2016–2022)Yuan-Ta Lin · C4 Therapeutics (United States)5 papers (2016–2020)Fatema Abdurrob · Massachusetts Institute of Technology3 papers (2016–2022)Jinsoo Seo · Yonsei University3 papers (2016–2018)Waseem Raja · Massachusetts Institute of Technology3 papers (2016–2018)Jemmie Cheng · Massachusetts Institute of Technology2 papers (2016–2018)Elizabeta Gjoneska · Massachusetts Institute of Technology2 papers (2016–2018)Fan Gao · University of Alabama at Birmingham2 papers (2016–2018)Dilip Dey · Massachusetts Institute of Technology2 papers (2017–2018)Hugh P. Cam · Centre International des Technologies de l'Environnement de Tunis2 papers (2018–2020)Oleg Kritskiy · Massachusetts Institute of Technology2 papers (2017–2018)Jay Penney · Massachusetts Institute of Technology2 papers (2017–2018)L. Ashley Watson · Massachusetts Institute of Technology2 papers (2017–2022)Steven D. Sheridan · Massachusetts Institute of Technology1 papers (2017–2017)Hiruy S. Meharena · University of California San Diego1 papers (2022–2022)Shruthi Rengarajan · Massachusetts Institute of Technology1 papers (2022–2022)Malvina Papanastasiou · Northeastern University1 papers (2022–2022)Sara Elmsaouri · University of California San Diego1 papers (2018–2018)Sukhee Cho · Daegu Gyeongbuk Institute of Science and Technology1 papers (2017–2017) · 1 papers (2017–2017)
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