Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Protein Kinase Regulation and GTPase Signaling, Microtubule and mitosis dynamics, Genomics and Chromatin Dynamics, and Neuroinflammation and Neurodegeneration Mechanisms.
Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration
Lipid accumulation induced by APOE4 impairs microglial surveillance of neuronal-network activity
Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors
Mapping the epigenomic and transcriptomic interplay during memory formation and recall in the hippocampal engram ensemble
Evolution of a dynamic molecular switch
Decoding the Interactions Regulating the Active State Mechanics of Eukaryotic Protein Kinases
Kinase Regulation by Hydrophobic Spine Assembly in Cancer
Allosteric Activation of Functionally Asymmetric RAF Kinase Dimers
Deciphering the Structural Basis of Eukaryotic Protein Kinase Regulation
Pseudokinases from a structural perspective