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Luigi Leanza

University of Padua · IT
Area of research
Molecular Biology · Sensory Systems
Research interest
Research interests include Mitochondrion, Cell biology, Potassium channel, Biology, Apoptosis, and Cancer research.
h-index
citations
2,316
works
42
NIH funding
primary concept
email

Recent publications

HSPA8 and HSPA9: Two prognostic and therapeutic targets in breast, colon, and kidney cancers?
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2025cited by 10position: lastdoi
The Role of Transglutaminase 2 in Cancer: An Update
International Journal of Molecular Sciences 2024cited by 28position: middledoi
BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway
Science Advances 2024cited by 17position: middledoi
Neural stem/progenitor cells from olfactory neuroepithelium collected by nasal brushing as a cell model reflecting molecular and cellular dysfunctions in schizophrenia
The World Journal of Biological Psychiatry 2024cited by 6position: middledoi
Human frataxin, the Friedreich ataxia deficient protein, interacts with mitochondrial respiratory chain
Cell Death and Disease 2023cited by 27position: middledoi
News and views on ion channels in cancer: is cancer a channelopathy?
Frontiers in Pharmacology 2023cited by 20position: middledoi
Pharmacological modulation of Kv1.3 potassium channel selectively triggers pathological B lymphocyte apoptosis in vivo in a genetic CLL model
Journal of Experimental & Clinical Cancer Research 2022cited by 38position: middledoi
Mitochondrial Dynamics, ROS, and Cell Signaling: A Blended Overview
Life 2021cited by 191position: middledoi
Mitochondrial K+ channels and their implications for disease mechanisms
Pharmacology & Therapeutics 2021cited by 56position: middledoi
A novel mitochondrial Kv1.3–caveolin axis controls cell survival and apoptosis
eLife 2021cited by 26position: middledoi
NMR Metabolite Profiles of the Bivalve Mollusc Mytilus galloprovincialis Before and After Immune Stimulation With Vibrio splendidus
Frontiers in Molecular Biosciences 2021cited by 24position: middledoi
Transglutaminase Type 2 regulates the Wnt/β-catenin pathway in vertebrates
Cell Death and Disease 2021cited by 23position: lastdoi
Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction
Nature Communications 2021cited by 23position: middledoi
Compensatory expression of NRF2-dependent antioxidant genes is required to overcome the lethal effects of Kv11.1 activation in breast cancer cells and PDOs
Redox Biology 2021cited by 19position: middledoi
Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family
Redox Biology 2020cited by 38position: middledoi
Mitochondrial Metabolism, Contact Sites and Cellular Calcium Signaling: Implications for Tumorigenesis
Cancers 2020cited by 37position: middledoi
Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction
Cell Reports 2019cited by 88position: lastdoi
Mitochondrial Kv1.3: a New Target in Cancer Biology?
Cellular Physiology and Biochemistry 2019cited by 29position: lastdoi
Targeting the Mitochondrial Potassium Channel Kv1.3 to Kill Cancer Cells: Drugs, Strategies, and New Perspectives
SLAS DISCOVERY 2019cited by 25position: lastdoi
Excessive Accumulation of Ca2 + in Mitochondria of Y522S-RYR1 Knock-in Mice: A Link Between Leak From the Sarcoplasmic Reticulum and Altered Redox State
Frontiers in Physiology 2019cited by 25position: middledoi
Pharmacological modulation of mitochondrial ion channels
British Journal of Pharmacology 2018cited by 48position: firstdoi
Mitochondrial apoptosis is induced by Alkoxy phenyl-1-propanone derivatives through PP2A-mediated dephosphorylation of Bad and Foxo3A in CLL
Leukemia 2018cited by 34position: middledoi
Novel Mitochondria-Targeted Furocoumarin Derivatives as Possible Anti-Cancer Agents
Frontiers in Oncology 2018cited by 29position: middledoi
Targeting Mitochondrial Ion Channels to Fight Cancer
International Journal of Molecular Sciences 2018cited by 25position: lastdoi
Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo
Cancer Cell 2017cited by 182position: firstdoi
Targeting the Potassium Channel Kv1.3 Kills Glioblastoma Cells
Neurosignals 2017cited by 50position: middledoi
Mitochondrial potassium channels in cell death
Biochemical and Biophysical Research Communications 2017cited by 37position: lastdoi
Regulation of Proliferation by a Mitochondrial Potassium Channel in Pancreatic Ductal Adenocarcinoma Cells
Frontiers in Oncology 2017cited by 21position: lastdoi
Physiology of intracellular potassium channels: A unifying role as mediators of counterion fluxes?
Biochimica et Biophysica Acta (BBA) - Bioenergetics 2016cited by 59position: middledoi
Tumor-reducing effect of the clinically used drug clofazimine in a SCID mouse model of pancreatic ductal adenocarcinoma
Oncotarget 2016cited by 54position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Ildikò Szabó · University of Padua27 papers (2012–2024)Mario Zoratti · University of Padua17 papers (2012–2022)Roberta Peruzzo · University of Padua14 papers (2016–2024)Erich Gulbins · Virginia Commonwealth University13 papers (2012–2024)Vanessa Checchetto · University of Padua9 papers (2012–2024)Lucia Biasutto · University of Padua7 papers (2013–2021)Roberto Costa · University of Padua7 papers (2018–2021)Livio Trentin · Veneto Institute of Molecular Medicine6 papers (2013–2022)Antonella Managò · University of Padua6 papers (2013–2020)Andrea Mattarei · University of Padua6 papers (2017–2022)Cristina Paradisi · University of Padua6 papers (2017–2022)Magdalena Bachmann · University of Padua6 papers (2018–2024)Gianpietro Semenzato · Tata Medical Center6 papers (2013–2022)Michele Azzolini · University of Padua5 papers (2016–2022)Silvia Muccioli · University of Padua4 papers (2021–2024)Elena Prosdocimi · University of Padua4 papers (2018–2024) · 3 papers (2013–2017)Federica Frezzato · University of Padua3 papers (2013–2022) · 3 papers (2014–2017)Matteo Romio · University of Padua3 papers (2017–2020)