Area of research
Molecular Biology · Pharmacology
Research interest
Research interests include Chemistry, Mitochondrion, Cell biology, Prodrug, Resveratrol, and Biology.
Small molecule OPA1 inhibitors amplify cytochrome c release and reverse cancer cells resistance to Bcl-2 inhibitors
Mitochondrial calcium uptake declines during aging and is directly activated by oleuropein to boost energy metabolism and skeletal muscle performance
The mitochondrial ATP-dependent potassium channel (mitoKATP) controls skeletal muscle structure and function
The Structural Dispersity of Oligoethylene Glycol-Containing Polymer Brushes Determines Their Interfacial Properties
Efficacy and Safety of Esmethadone (REL-1017) in Patients With Major Depressive Disorder and Inadequate Response to Standard Antidepressants
Esmethadone-HCl (REL-1017): a promising rapid antidepressant
Defective excitation-contraction coupling and mitochondrial respiration precede mitochondrial Ca2+ accumulation in spinobulbar muscular atrophy skeletal muscle
Pharmacological modulation of Kv1.3 potassium channel selectively triggers pathological B lymphocyte apoptosis in vivo in a genetic CLL model
Pharmacological Comparative Characterization of REL-1017 (Esmethadone-HCl) and Other NMDAR Channel Blockers in Human Heterodimeric N-Methyl-D-Aspartate Receptors
Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo
Inhibition of a Mitochondrial Potassium Channel in Combination with Gemcitabine and Abraxane Drastically Reduces Pancreatic Ductal Adenocarcinoma in an Immunocompetent Orthotopic Murine Model
Esmethadone (REL-1017) and Other Uncompetitive NMDAR Channel Blockers May Improve Mood Disorders via Modulation of Synaptic Kinase-Mediated Signaling
Dispersity within Brushes Plays a Major Role in Determining Their Interfacial Properties: The Case of Oligoxazoline-Based Graft Polymers
Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD
Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family
Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction
A Synthetic Fluorescent Mitochondria‐Targeted Sensor for Ratiometric Imaging of Calcium in Live Cells
A CXCR4 receptor agonist strongly stimulates axonal regeneration after damage
pH-Controlled Liposomes for Enhanced Cell Penetration in Tumor Environment
Novel Mitochondria-Targeted Furocoumarin Derivatives as Possible Anti-Cancer Agents
Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo
LETM1-Mediated K+ and Na+ Homeostasis Regulates Mitochondrial Ca2+ Efflux
Resveratrol derivatives as a pharmacological tool
Targeting the Potassium Channel Kv1.3 Kills Glioblastoma Cells
Regulation of Proliferation by a Mitochondrial Potassium Channel in Pancreatic Ductal Adenocarcinoma Cells
A Photo‐Crosslinkable Biotin Derivative of the Phosphoantigen (<i>E</i>)‐4‐Hydroxy‐3‐Methylbut‐2‐Enyl Diphosphate (HMBPP) Activates Vγ9Vδ2 T Cells and Binds to the HMBPP Site of BTN3A1
Hsp90 is involved in the entry of clostridial neurotoxins into the cytosol of nerve terminals
Amino Acid Carbamates As Prodrugs Of Resveratrol
Synthesis and Evaluation as Prodrugs of Hydrophilic Carbamate Ester Analogues of Resveratrol
Pharmacokinetics and tissue distribution of pterostilbene in the rat