Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Ubiquitin and proteasome pathways, Protein Degradation and Inhibitors, Chemical Synthesis and Analysis, and Hippo pathway signaling and YAP/TAZ.
Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)–Mixed Lineage Leukemia (MLL) Protein–Protein Interaction
MLL1 and MLL1 fusion proteins have distinct functions in regulating leukemic transcription program
Targeting MLL1 H3K4 Methyltransferase Activity in Mixed-Lineage Leukemia
High-Affinity, Small-Molecule Peptidomimetic Inhibitors of MLL1/WDR5 Protein–Protein Interaction
Structure-Based Design of High-Affinity Macrocyclic Peptidomimetics to Block the Menin-Mixed Lineage Leukemia 1 (MLL1) Protein–Protein Interaction