Area of research
Endocrinology · Molecular Biology
Research interest
Research interests include Escherichia coli research studies, Gut microbiota and health, Virus-based gene therapy research, and Viral gastroenteritis research and epidemiology.
Blood group A enhances SARS-CoV-2 infection
Blood group A enhances SARS-CoV-2 infection.
The host-directed therapeutic imatinib mesylate accelerates immune responses to Mycobacterium marinum infection and limits pathology associated with granulomas.
A microbiota and dietary metabolite integrates DNA repair and cell death to regulate embryo viability and aneuploidy during aging.
The immunoregulatory landscape of human tuberculosis granulomas
Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis
The SARS-CoV-2 receptor-binding domain preferentially recognizes blood group A
The SARS-CoV-2 receptor-binding domain preferentially recognizes blood group A.
Indoles from the commensal microbiota act via the AHR and IL-10 to tune the cellular composition of the colonic epithelium during aging
Competition between E3 and ZBP1 for Z-RNA Dictates Susceptibility to Vaccinia Virus-Induced Necroptosis
IMPACT-TB*: A Phase II Trial Assessing the Capacity of Low Dose Imatinib to Induce Myelopoiesis and Enhance Host Anti-Microbial Immunity Against Tuberculosis. *Imatinib Mesylate per Oral As a Clinical Therapeutic for TB
Indoles derived from intestinal microbiota act via type I interferon signaling to limit graft-versus-host disease
The Evasive Enemy: Insights into the Virulence and Epidemiology of the Emerging Attaching and Effacing Pathogen<i>Escherichia albertii</i>
Preclinical pharmacokinetic evaluation to facilitate repurposing of tyrosine kinase inhibitors nilotinib and imatinib as antiviral agents
Layered defense: how mucus and tight junctions seal the intestinal barrier
In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of<i>Mycobacterium tuberculosis</i>
Indoles from commensal bacteria extend healthspan
Inhibition of DAI-dependent necroptosis by the Z-DNA binding domain of the vaccinia virus innate immune evasion protein, E3
Monocarbonyl analogs of curcumin inhibit growth of antibiotic sensitive and resistant strains of Mycobacterium tuberculosis
Low Doses of Imatinib Induce Myelopoiesis and Enhance Host Anti-microbial Immunity
New tricks for old dogs: countering antibiotic resistance in tuberculosis with host‐directed therapeutics
A Family of Indoles Regulate Virulence and Shiga Toxin Production in Pathogenic E. coli
Intestinal Epithelial CD98 Directly Modulates the Innate Host Response to Enteric Bacterial Pathogens
Productive Replication of Ebola Virus Is Regulated by the c-Abl1 Tyrosine Kinase