Area of research
Molecular Biology · Rheumatology
Research interest
Research interests include Folate and B Vitamins Research, Porphyrin Metabolism and Disorders, Sulfur Compounds in Biology, and Metabolism and Genetic Disorders.
Hydrogen sulfide–dependent activation of human sulfide quinone oxidoreductase
Differential utilization of vitamin B12-dependent and independent pathways for propionate metabolism across human cells
An Interprotein Co–S Coordination Complex in the B<sub>12</sub>-Trafficking Pathway
Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair
Sacrificial Cobalt–Carbon Bond Homolysis in Coenzyme B<sub>12</sub> as a Cofactor Conservation Strategy
Chemical Biology of H<sub>2</sub>S Signaling through Persulfidation
The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B12
Antivitamin B<sub>12</sub> Inhibition of the Human B<sub>12</sub>‐Processing Enzyme CblC: Crystal Structure of an Inactive Ternary Complex with Glutathione as the Cosubstrate
Visualization of a radical B <sub>12</sub> enzyme with its G-protein chaperone
Structural Basis for Substrate Specificity in Adenosylcobalamin-dependent Isobutyryl-CoA Mutase and Related Acyl-CoA Mutases