Area of research
Immunology · Infectious Diseases
Research interest
Research interests include interferon and immune responses, Viral Infections and Vectors, Virus-based gene therapy research, and Inflammasome and immune disorders.
Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production
Pro-inflammation Associated with a Gain-of-Function Mutation (R284S) in the Innate Immune Sensor STING
Ubiquitination of STING at lysine 224 controls IRF3 activation
Activation of STING requires palmitoylation at the Golgi
Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis
Diverse roles of STING-dependent signaling on the development of cancer
Active IKKβ promotes the stability of GLI1 oncogene in diffuse large B-cell lymphoma
Inflammation-driven carcinogenesis is mediated through STING
The STING controlled cytosolic-DNA activated innate immune pathway and microbial disease
Cyclic Dinucleotides Trigger ULK1 (ATG1) Phosphorylation of STING to Prevent Sustained Innate Immune Signaling
STING Recognition of Cytoplasmic DNA Instigates Cellular Defense