Area of research
Endocrinology, Diabetes and Metabolism · Molecular Biology
Research interest
Research interests include Pituitary Gland Disorders and Treatments, Growth Hormone and Insulin-like Growth Factors, Pluripotent Stem Cells Research, and Congenital heart defects research.
EndoCompass project: research roadmap for pituitary and neuroendocrine tumor endocrinology
EndoCompass Project: Research Roadmap for Pituitary and Neuroendocrine Tumor Endocrinology
EndoCompass project: research roadmap for reproductive and developmental endocrinology
Intratumoral pan-ErbB targeted CAR-T for head and neck squamous cell carcinoma: interim analysis of the T4 immunotherapy study
The Fuzzy planar cell polarity protein (<scp>FUZ</scp>), necessary for primary cilium formation, is essential for pituitary development
Single nucleus transcriptome and chromatin accessibility of postmortem human pituitaries reveal diverse stem cell regulatory mechanisms
Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation
Loss of SDHB Promotes Dysregulated Iron Homeostasis, Oxidative Stress, and Sensitivity to Ascorbate
Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells
TGFBR3L is an inhibin B co-receptor that regulates female fertility
Insulin and obesity transform hypothalamic-pituitary-adrenal axis stemness and function in a hyperactive state
Biological Behaviour of Craniopharyngiomas
Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade
Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target
Isolation and characterization of adrenocortical progenitors involved in the adaptation to stress
Stress-inducible-stem cells: a new view on endocrine, metabolic and mental disease?
Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma
MAPK pathway activation in the embryonic pituitary results in stem cell compartment expansion, differentiation defects and provides insights into the pathogenesis of papillary craniopharyngioma
Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors
Two missense mutations in KCNQ1 cause pituitary hormone deficiency and maternally inherited gingival fibromatosis
Transcription factor 7-like 1 is involved in hypothalamo–pituitary axis development in mice and humans
Expression Analysis of the Hippo Cascade Indicates a Role in Pituitary Stem Cell Development
Concise Review: Paracrine Role of Stem Cells in Pituitary Tumors: A Focus on Adamantinomatous Craniopharyngioma
Activated WNT signaling in postnatal SOX2-positive dental stem cells can drive odontoma formation
CHD7 Maintains Neural Stem Cell Quiescence and Prevents Premature Stem Cell Depletion in the Adult Hippocampus
The role of the sonic hedgehog signalling pathway in patients with midline defects and congenital hypopituitarism
Establishment of the neurogenic boundary of the mouse retina requires cooperation of SOX2 and WNT signaling