Area of research
Endocrinology, Diabetes and Metabolism · Molecular Biology
Research interest
Research interests include Pituitary Gland Disorders and Treatments, Glioma Diagnosis and Treatment, Hedgehog Signaling Pathway Studies, and Retinoids in leukemia and cellular processes.
Unraveling the complexity of the senescence-associated secretory phenotype in adamantinomatous craniopharyngioma using multimodal machine learning analysis
Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer
Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target
Biomedical Research in Aging
Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma
Molecular Analyses Reveal Inflammatory Mediators in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma
MAPK pathway activation in the embryonic pituitary results in stem cell compartment expansion, differentiation defects and provides insights into the pathogenesis of papillary craniopharyngioma
Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors