Michael Caffrey

Mechanistic insights into the small-molecule inhibition of influenza A virus entry

An orally active entry inhibitor of influenza A viruses protects mice and synergizes with oseltamivir and baloxavir marboxil

Towards real-time airborne pathogen sensing: Electrostatic capture and on-chip LAMP based detection of airborne viral pathogens

Small Molecule Inhibitors of Influenza Virus Entry

pH-Dependent Mechanisms of Influenza Infection Mediated by Hemagglutinin

Evidence for distinct mechanisms of small molecule inhibitors of filovirus entry

Structure of avian influenza hemagglutinin in complex with a small molecule entry inhibitor

Optimization of 4-Aminopiperidines as Inhibitors of Influenza A Viral Entry That Are Synergistic with Oseltamivir

Identification of entry inhibitors with 4-aminopiperidine scaffold targeting group 1 influenza A virus

NMR-based metabolite studies with 15N amino acids

Identification of a pH sensor in Influenza hemagglutinin using X-ray crystallography

A Novel <scp>l</scp> -Asparaginase with low <scp>l</scp> -Glutaminase Coactivity Is Highly Efficacious against Both T- and B-cell Acute Lymphoblastic Leukemias <i>In Vivo</i>

Aniline-Based Inhibitors of Influenza H1N1 Virus Acting on Hemagglutinin-Mediated Fusion

A Chemical Probe Strategy for Interrogating Inhibitor Selectivity Across the MEK Kinase Family

Molecular Mechanism Underlying the Action of Influenza A Virus Fusion Inhibitor MBX2546

Experimental Data in Support of a Direct Displacement Mechanism for Type I/II l-Asparaginases

Application of virus-like particles (VLP) to NMR characterization of viral membrane protein interactions

Structural Basis of a Key Factor Regulating the Affinity between the Zonula Occludens First PDZ Domain and Claudins

Identification of a Broad-Spectrum Antiviral Small Molecule against Severe Acute Respiratory Syndrome Coronavirus and Ebola, Hendra, and Nipah Viruses by Using a Novel High-Throughput Screening Assay

Comparison of the sensitivities of WaterLOGSY and saturation transfer difference NMR experiments

Mutagenesis Studies of the H5 Influenza Hemagglutinin Stem Loop Region

Discovery of Selective Inhibitors of the Clostridium difficile Dehydroquinate Dehydratase

New Small Molecule Entry Inhibitors Targeting Hemagglutinin-Mediated Influenza A Virus Fusion

Inhibition of Influenza H7 Hemagglutinin-Mediated Entry

Characterization of Influenza Hemagglutinin Interactions with Receptor by NMR

Residue Y161 of Influenza Virus Hemagglutinin Is Involved in Viral Recognition of Sialylated Complexes from Different Hosts