Area of research
Cardiology and Cardiovascular Medicine · Molecular Biology
Research interest
Research interests include Biology, Viral replication, Coxsackievirus, Enterovirus, Cell biology, and Virology.
Dynamic remodelling of the human host cell proteome and phosphoproteome upon enterovirus infection
Synthesis and antiviral effect of novel fluoxetine analogues as enterovirus 2C inhibitors
Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C
Fluoxetine Inhibits Enterovirus Replication by Targeting the Viral 2C Protein in a Stereospecific Manner
ACBD3 Is an Essential Pan-enterovirus Host Factor That Mediates the Interaction between Viral 3A Protein and Cellular Protein PI4KB
Characterization of the c10orf76‐PI4KB complex and its necessity for Golgi PI4P levels and enterovirus replication
Convergent evolution in the mechanisms of ACBD3 recruitment to picornavirus replication sites
The life cycle of non-polio enteroviruses and how to target it
Posaconazole inhibits dengue virus replication by targeting oxysterol-binding protein
Viral rewiring of cellular lipid metabolism to create membranous replication compartments
Direct-acting antivirals and host-targeting strategies to combat enterovirus infections
Uncovering oxysterol-binding protein (OSBP) as a target of the anti-enteroviral compound TTP-8307
Building Viral Replication Organelles: Close Encounters of the Membrane Types
Fat(al) attraction: Picornaviruses Usurp Lipid Transfer at Membrane Contact Sites to Create Replication Organelles
Mutations in Encephalomyocarditis Virus 3A Protein Uncouple the Dependency of Genome Replication on Host Factors Phosphatidylinositol 4-Kinase IIIα and Oxysterol-Binding Protein
Illuminating the Sites of Enterovirus Replication in Living Cells by Using a Split-GFP-Tagged Viral Protein
Itraconazole Inhibits Enterovirus Replication by Targeting the Oxysterol-Binding Protein
Modulation of the Host Lipid Landscape to Promote RNA Virus Replication: The Picornavirus Encephalomyocarditis Virus Converges on the Pathway Used by Hepatitis C Virus
Broad-range inhibition of enterovirus replication by OSW-1, a natural compound targeting OSBP
Cholesterol shuttling is important for <scp>RNA</scp> replication of coxsackievirus <scp>B</scp> 3 and encephalomyocarditis virus
Recruitment of PI4KIIIβ to Coxsackievirus B3 Replication Organelles Is Independent of ACBD3, GBF1, and Arf1
Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication