Area of research
Cardiology and Cardiovascular Medicine · Infectious Diseases
Research interest
Research interests include Biology, Virology, Coronavirus, Viral replication, Cell biology, and RNA.
MFSD6 is an entry receptor for enterovirus D68
A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein
A coronavirus assembly inhibitor that targets the viral membrane protein
Safety and efficacy of live attenuated PEDV vaccines for neonatal protection
The activation of the adaptor protein STING depends on its interactions with the phospholipid PI4P
Nanoparticle display of neuraminidase elicits enhanced antibody responses and protection against influenza A virus challenge
Safety concern of recombination between self-amplifying mRNA vaccines and viruses is mitigated in vivo
Modulation of nucleotide metabolism by picornaviruses
Highly pathogenic avian influenza (HPAI) H5 virus exposure in domestic cats and rural stray cats, the Netherlands, October 2020 to June 2023
Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein
Assessment of Kinome-Wide Activity Remodeling upon Picornavirus Infection
Sialoglycan binding triggers spike opening in a human coronavirus
Antiviral responses are shaped by heterogeneity in viral replication dynamics
H3N2 influenza A virus gradually adapts to human-type receptor binding and entry specificity after the start of the 1968 pandemic
A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein
Gradual adaptation of animal influenza A viruses to human-type sialic acid receptors
SARS-CoV-2 nucleocapsid protein inhibits the PKR-mediated integrated stress response through RNA-binding domain N2b
Mathematical modeling of plus-strand RNA virus replication to identify broad-spectrum antiviral treatment strategies
Kinetic analysis of paramyxovirus-sialoglycan receptor interactions reveals virion motility
Neuraminidase-dependent entry of influenza A virus is determined by hemagglutinin receptor-binding specificity
Human-type sialic acid receptors contribute to avian influenza A virus binding and entry by hetero-multivalent interactions
An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern
The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants
Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes
Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex
The encephalomyocarditis virus Leader promotes the release of virions inside extracellular vesicles via the induction of secretory autophagy
Enterovirus D68 Infection in Human Primary Airway and Brain Organoids: No Additional Role for Heparan Sulfate Binding for Neurotropism
Antiviral treatment with fluoxetine for rituximab‐associated chronic echovirus 13 meningoencephalitis and myofasciitis
A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies
SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms