Area of research
Infectious Diseases · Animal Science and Zoology
Research interest
Research interests include SARS-CoV-2 and COVID-19 Research, Animal Virus Infections Studies, Viral gastroenteritis research and epidemiology, and Virus-based gene therapy research.
A coronavirus assembly inhibitor that targets the viral membrane protein
Safety and efficacy of live attenuated PEDV vaccines for neonatal protection
Genome-wide CRISPR screen reveals key role of sialic acids in PEDV and porcine coronavirus infections
Nanoparticle display of neuraminidase elicits enhanced antibody responses and protection against influenza A virus challenge
Functional dissection of the spike glycoprotein S1 subunit and identification of cellular cofactors for regulation of swine acute diarrhea syndrome coronavirus entry
Genome-wide CRISPR/Cas9 library screen identifies C16orf62 as a host dependency factor for porcine deltacoronavirus infection
Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein
Filamentous fungus-produced human monoclonal antibody provides protection against SARS-CoV-2 in hamster and non-human primate models
Sialoglycan binding triggers spike opening in a human coronavirus
Glycosylated extracellular mucin domains protect against SARS-CoV-2 infection at the respiratory surface
A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein
Genetic analysis of infectious bronchitis virus (IBV) in vaccinated poultry populations over a period of 10 years
An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern
The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants
Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes
Suitability of transiently expressed antibodies for clinical studies: product quality consistency at different production scales
Structural basis for broad coronavirus neutralization
A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies
SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms
A plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays
Serologic Screening of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Cats and Dogs during First Coronavirus Disease Wave, the Netherlands
Dynamics of antibodies to SARS‐CoV‐2 in convalescent plasma donors
Human Milk from Previously COVID-19-Infected Mothers: The Effect of Pasteurization on Specific Antibodies and Neutralization Capacity
Structural insights into the cross-neutralization of SARS-CoV and SARS-CoV-2 by the human monoclonal antibody 47D11
A highly potent antibody effective against SARS-CoV-2 variants of concern
SARS-CoV-2 Neutralizing Human Antibodies Protect Against Lower Respiratory Tract Disease in a Hamster Model
An alphavirus replicon-based vaccine expressing a stabilized Spike antigen induces protective immunity and prevents transmission of SARS-CoV-2 between cats
Severe Acute Respiratory Syndrome Coronavirus 2−Specific Antibody Responses in Coronavirus Disease Patients
A human monoclonal antibody blocking SARS-CoV-2 infection
Changes in SARS-CoV-2 Spike versus Nucleoprotein Antibody Responses Impact the Estimates of Infections in Population-Based Seroprevalence Studies