Area of research
Pathology and Forensic Medicine · Neurology
Research interest
Research interests include Multiple sclerosis, Pathology, Medicine, Inflammation, Microglia, and Grey matter.
Intrathecal Inflammatory Profile and Gray Matter Damage Predict Progression Independent of Relapse Activity in Early Multiple Sclerosis
Mapping Molecular Pathways of Multiple Sclerosis: A Gene Prioritization and Network Analysis of White Matter Pathology Transcriptomics
Sterol imbalances and cholesterol‐24‐hydroxylase dysregulation is linked to the underlying progression of multiple sclerosis
Spatial transcriptomics of compartmentalised inflammation in a natural disease multiple sclerosis cohort
Determinants and Biomarkers of Progression Independent of Relapses in Multiple Sclerosis
Neuropathological and cerebrospinal fluid correlates of choroid plexus inflammation in progressive multiple sclerosis
Digital Pathology Identifies Associations between Tissue Inflammatory Biomarkers and Multiple Sclerosis Outcomes
Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases
Meningeal inflammation as a driver of cortical grey matter pathology and clinical progression in multiple sclerosis
Comparing the Pathology, Clinical, and Demographic Characteristics of Younger and Older‐Onset Multiple Sclerosis
Complement activation and increased anaphylatoxin receptor expression are associated with cortical grey matter lesions and the compartmentalised inflammatory response of multiple sclerosis
High Levels of Perivascular Inflammation and Active Demyelinating Lesions at Time of Death Associated with Rapidly Progressive Multiple Sclerosis Disease Course: A Retrospective Postmortem Cohort Study
Inhibition of 7α,26-dihydroxycholesterol biosynthesis promotes midbrain dopaminergic neuron development
“Ependymal‐in” Gradient of Thalamic Damage in Progressive Multiple Sclerosis
The association between neurodegeneration and local complement activation in the thalamus to progressive multiple sclerosis outcome
A Review of Compartmentalised Inflammation and Tertiary Lymphoid Structures in the Pathophysiology of Multiple Sclerosis
A multicentre, open label, single-arm, phase 3b study (CONSONANCE) to assess the effectiveness and safety of ocrelizumab in patients with primary and secondary progressive multiple sclerosis: year-1 interim analysis (P1-1.Virtual)
A multicenter, open label, single-arm, phase 3b study (CONSONANCE) to assess efficacy of ocrelizumab in patients with primary and secondary progressive multiple sclerosis: year 1 interim analysis of cognition outcomes (P1-1.Virtual)
Analysis of target mRNAs in the fixed-frozen human brain using a modified BaseScope-ISH Assay protocol
Visualizing Cholesterol in the Brain by On-Tissue Derivatization and Quantitative Mass Spectrometry Imaging
Metabolic profiling in serum, cerebrospinal fluid, and brain of patients with cerebrotendinous xanthomatosis
B cell rich meningeal inflammation associates with increased spinal cord pathology in multiple sclerosis
Localization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism
Neuroinflammation in the normal-appearing white matter (NAWM) of the multiple sclerosis brain causes abnormalities at the nodes of Ranvier
Unacylated-Ghrelin Impairs Hippocampal Neurogenesis and Memory in Mice and Is Altered in Parkinson’s Dementia in Humans
Substantial subpial cortical demyelination in progressive multiple sclerosis: have we underestimated the extent of cortical pathology?
CCN3 is dynamically regulated by treatment and disease state in multiple sclerosis
Neuroinflammation in the normal appearing white matter of multiple sclerosis brain causes abnormalities at the node of Ranvier
Visualising Cholesterol in Brain by On-Tissue Derivatisation and Quantitative Mass Spectrometry Imaging
Meningeal inflammation changes the balance of TNF signalling in cortical grey matter in multiple sclerosis