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Joel E. Kleinman

Johns Hopkins University · US
Area of research
Cellular and Molecular Neuroscience · Genetics
Research interest
Research interests include Neuroscience and Neuropharmacology Research, Genetic Associations and Epidemiology, Schizophrenia research and treatment, and Neurotransmitter Receptor Influence on Behavior.
h-index
95
citations
35,269
works
559
NIH funding
primary concept
email

Recent publications

Single-cell multi-cohort dissection of the schizophrenia transcriptome
Science 2024cited by 125position: middledoi
Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood
Science 2024cited by 81position: middledoi
Massively parallel characterization of regulatory elements in the developing human cortex
Science 2024cited by 61position: middledoi
Cross-ancestry atlas of gene, isoform, and splicing regulation in the developing human brain
Science 2024cited by 46position: middledoi
Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: a meta-analysis of 23 military and civilian cohorts
Genome Medicine 2024cited by 21position: middledoi
Transcriptomic sex differences in postmortem brain samples from patients with psychiatric disorders
Science Translational Medicine 2024cited by 20position: middledoi
Dopamine signaling enriched striatal gene set predicts striatal dopamine synthesis and physiological activity in vivo
Nature Communications 2024cited by 15position: middledoi
Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing
Nature Genetics 2023cited by 55position: middledoi
W77. ENHANCING GENE EXPRESSION PREDICTION IN MAJOR PSYCHIATRIC DISORDERS VIA CO-EXPRESSION MODELS
European Neuropsychopharmacology 2023cited by 0position: middledoi
Molecular landscapes of human hippocampal immature neurons across lifespan
Nature 2022cited by 304position: middledoi
Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability
Science 2022cited by 71position: middledoi
A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespan
Cell stem cell 2022cited by 66position: middledoi
Decoding Shared Versus Divergent Transcriptomic Signatures Across Cortico-Amygdala Circuitry in PTSD and Depressive Disorders
American Journal of Psychiatry 2022cited by 55position: lastdoi
Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex
Nature Neuroscience 2021cited by 1,193position: middledoi
Single-nucleus transcriptome analysis reveals cell-type-specific molecular signatures across reward circuitry in the human brain
Neuron 2021cited by 228position: middledoi
Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs
Nature Communications 2020cited by 195position: middledoi
Sex differences in the transcription of glutamate transporters in major depression and suicide.
Journal of Affective Disorders 2020cited by 20position: middledoi
Regional Heterogeneity in Gene Expression, Regulation, and Coherence in the Frontal Cortex and Hippocampus across Development and Schizophrenia
Neuron 2019cited by 240position: middledoi
Integrated DNA methylation and gene expression profiling across multiple brain regions implicate novel genes in Alzheimer’s disease
Acta Neuropathologica 2019cited by 120position: middledoi
NURR1 and ERR1 Modulate the Expression of Genes of a<i>DRD2</i>Coexpression Network Enriched for Schizophrenia Risk
Journal of Neuroscience 2019cited by 25position: middledoi
Integrative functional genomic analysis of human brain development and neuropsychiatric risks
Science 2018cited by 870position: middledoi
Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis
Nature Neuroscience 2018cited by 398position: middledoi
Identification and prioritization of gene sets associated with schizophrenia risk by co-expression network analysis in human brain
Molecular Psychiatry 2018cited by 116position: middledoi
Variations in Dysbindin-1 are associated with cognitive response to antipsychotic drug treatment
Nature Communications 2018cited by 42position: middledoi
Molecular and cellular reorganization of neural circuits in the human lineage
Science 2017cited by 266position: middledoi
Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder
Molecular Psychiatry 2017cited by 146position: middledoi
qSVA framework for RNA quality correction in differential expression analysis
Proceedings of the National Academy of Sciences 2017cited by 132position: middledoi
Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons
Cell stem cell 2016cited by 832position: middledoi
Dynamic regulation of RNA editing in human brain development and disease
Nature Neuroscience 2016cited by 201position: middledoi
Association of DNA Methylation Differences With Schizophrenia in an Epigenome-Wide Association Study
JAMA Psychiatry 2016cited by 183position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Thomas M. Hyde · Johns Hopkins University27 papers (2012–2024)Daniel R. Weinberger · Johns Hopkins University20 papers (2012–2024)Joo Heon Shin · Lieber Institute for Brain Development12 papers (2014–2024)Andrew E. Jaffe · Johns Hopkins University12 papers (2014–2022)Ran Tao · Vanderbilt University10 papers (2012–2022)Richard E. Straub · Lieber Institute for Brain Development7 papers (2012–2019)Amy Deep‐Soboslay · Lieber Institute for Brain Development6 papers (2015–2022)Leonardo Collado‐Torres · L&S Consulting (South Africa)6 papers (2014–2021)Qiang Chen · Jiangsu University4 papers (2016–2024)Yuan Gao · Hebei Agricultural University4 papers (2014–2018)Jeffrey T. Leek · BioScience Laboratories (United States)3 papers (2014–2018)Kristen R. Maynard · Johns Hopkins University3 papers (2021–2022)Giulio Pergola · University of Oslo3 papers (2019–2024)Barbara K. Lipska · National Human Genome Research Institute3 papers (2012–2014) · 3 papers (2019–2024)Yankai Jia · Johns Hopkins Medicine3 papers (2014–2017)William S. Ulrich · Lieber Institute for Brain Development3 papers (2018–2024)Keri Martinowich · Johns Hopkins University3 papers (2021–2022)Guo‐li Ming · University of Pennsylvania3 papers (2014–2022)Brady J. Maher · Johns Hopkins University3 papers (2014–2018)