Area of research
Molecular Biology
Research interest
Research interests include Single-cell and spatial transcriptomics, Molecular Biology Techniques and Applications, Gene expression and cancer classification, and RNA Research and Splicing.
Single-cell multi-cohort dissection of the schizophrenia transcriptome
Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood
Massively parallel characterization of regulatory elements in the developing human cortex
Cross-ancestry atlas of gene, isoform, and splicing regulation in the developing human brain
Transcriptomic sex differences in postmortem brain samples from patients with psychiatric disorders
spatialLIBD: an R/Bioconductor package to visualize spatially-resolved transcriptomics data
SpatialExperiment: infrastructure for spatially-resolved transcriptomics data in R using Bioconductor
Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex
recount3: summaries and queries for large-scale RNA-seq expression and splicing
Single-nucleus transcriptome analysis reveals cell-type-specific molecular signatures across reward circuitry in the human brain
Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders
SpatialExperiment: infrastructure for spatially resolved transcriptomics data in R using Bioconductor
Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs
Incomplete annotation has a disproportionate impact on our understanding of Mendelian and complex neurogenetic disorders
Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information
Regional Heterogeneity in Gene Expression, Regulation, and Coherence in the Frontal Cortex and Hippocampus across Development and Schizophrenia
Integrated DNA methylation and gene expression profiling across multiple brain regions implicate novel genes in Alzheimer’s disease
Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder
Comprehensive functional genomic resource and integrative model for the human brain
Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis
Reproducible RNA-seq analysis using recount2
Human splicing diversity and the extent of unannotated splice junctions across human RNA-seq samples on the Sequence Read Archive
Rail-RNA: scalable analysis of RNA-seq splicing and coverage
Developmental regulation of human cortex transcription and its clinical relevance at single base resolution