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Jeffrey T. Leek

BioScience Laboratories (United States) · US
Area of research
Molecular Biology · Information Systems and Management
Research interest
Research interests include Gene expression and cancer classification, Scientific Computing and Data Management, Molecular Biology Techniques and Applications, and Bioinformatics and Genomic Networks.
h-index
54
citations
30,915
works
199
NIH funding
primary concept
email

Recent publications

Inverting the model of genomics data sharing with the NHGRI Genomic Data Science Analysis, Visualization, and Informatics Lab-space
Cell Genomics 2022cited by 128position: middledoi
recount3: summaries and queries for large-scale RNA-seq expression and splicing
Genome biology 2021cited by 278position: middledoi
Transparency and reproducibility in artificial intelligence
Nature 2020cited by 489position: middledoi
Addressing confounding artifacts in reconstruction of gene co-expression networks
Genome biology 2019cited by 116position: lastdoi
Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis
Nature Neuroscience 2018cited by 398position: middledoi
Reproducible RNA-seq analysis using recount2
Nature Biotechnology 2017cited by 528position: lastdoi
qSVA framework for RNA quality correction in differential expression analysis
Proceedings of the National Academy of Sciences 2017cited by 132position: middledoi
Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown
Nature Protocols 2016cited by 7,537position: middledoi
What Should Researchers Expect When They Replicate Studies? A Statistical View of Replicability in Psychological Science
Perspectives on Psychological Science 2016cited by 261position: lastdoi
Human splicing diversity and the extent of unannotated splice junctions across human RNA-seq samples on the Sequence Read Archive
Genome biology 2016cited by 121position: lastdoi
BatchQC: interactive software for evaluating sample and batch effects in genomic data
Bioinformatics 2016cited by 67position: middledoi
Rail-RNA: scalable analysis of RNA-seq splicing and coverage
Bioinformatics 2016cited by 65position: middledoi
Ballgown bridges the gap between transcriptome assembly and expression analysis
Nature Biotechnology 2015cited by 913position: lastdoi
<i>Polyester</i> : simulating RNA-seq datasets with differential transcript expression
Bioinformatics 2015cited by 364position: lastdoi
Statistics: P values are just the tip of the iceberg
Nature 2015cited by 217position: firstdoi
Reproducible research can still be wrong: Adopting a prevention approach
Proceedings of the National Academy of Sciences 2015cited by 200position: firstdoi
Evolution of cellular morpho-phenotypes in cancer metastasis
Scientific Reports 2015cited by 135position: middledoi
Test set bias affects reproducibility of gene signatures
Bioinformatics 2015cited by 123position: lastdoi
svaseq: removing batch effects and other unwanted noise from sequencing data
Nucleic Acids Research 2014cited by 583position: firstdoi
Developmental regulation of human cortex transcription and its clinical relevance at single base resolution
Nature Neuroscience 2014cited by 170position: middledoi
Preserving biological heterogeneity with a permuted surrogate variable analysis for genomics batch correction
Bioinformatics 2014cited by 140position: middledoi
An estimate of the science-wise false discovery rate and application to the top medical literature
Biostatistics 2013cited by 190position: lastdoi
The <tt>sva</tt> package for removing batch effects and other unwanted variation in high-throughput experiments
Bioinformatics 2012cited by 6,645position: firstdoi
Bump hunting to identify differentially methylated regions in epigenetic epidemiology studies
International Journal of Epidemiology 2012cited by 768position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Andrew E. Jaffe · Johns Hopkins University12 papers (2012–2021)Leonardo Collado‐Torres · L&S Consulting (South Africa)6 papers (2014–2021)Ben Langmead · Johns Hopkins University6 papers (2015–2021)Abhinav Nellore · NYU Langone Health5 papers (2016–2021)Roger D. Peng · The University of Texas at Austin3 papers (2015–2016)Daniel R. Weinberger · Johns Hopkins University3 papers (2014–2018)Kasper D. Hansen · University of Baltimore3 papers (2016–2021)Thomas M. Hyde · Johns Hopkins University3 papers (2014–2018)Ran Tao · Vanderbilt University3 papers (2014–2018)Joel E. Kleinman · Johns Hopkins University3 papers (2014–2018)W. Evan Johnson · Center for Translational Molecular Medicine2 papers (2012–2016)Joo Heon Shin · Lieber Institute for Brain Development2 papers (2017–2018)Christopher Wilks · Johns Hopkins University2 papers (2016–2021) · 2 papers (2016–2019)José Alquicira-Hernández · Broad Institute2 papers (2016–2016)Geo Pertea · McLean Hospital2 papers (2015–2016)Richard E. Straub · Lieber Institute for Brain Development2 papers (2017–2018)Yuan Gao · Hebei Agricultural University2 papers (2014–2018)Yankai Jia · Johns Hopkins Medicine2 papers (2014–2017)Prasad Patil · Boston University2 papers (2015–2016)