Area of research
Physiology · Psychiatry and Mental health
Research interest
Research interests include Alzheimer's disease research and treatments, Dementia and Cognitive Impairment Research, Metabolomics and Mass Spectrometry Studies, and Bioinformatics and Genomic Networks.
Depressive Symptoms and Amyloid Pathology
Machine learning in Alzheimer’s disease genetics
Cerebrospinal fluid proteomic associations of <i>APOE</i> genotypes reveal distinct protective and risk mechanisms for Alzheimer's disease
The association of diabetes with Alzheimer's disease biomarkers and vascular burden across European aging and memory clinic cohorts
Involvement of the choroid plexus in Alzheimer’s disease pathophysiology: findings from mouse and human proteomic studies
Blood‐based multivariate methylation risk score for cognitive impairment and dementia
Blood DNA methylomic signatures associated with CSF biomarkers of Alzheimer's disease in the EMIF‐AD study
Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease
Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by <i>HLA-DRB1*04</i> subtypes
Blood DNA methylomic signatures associated with CSF biomarkers of Alzheimer’s disease in the EMIF‐AD Multimodal Biomarker Discovery study
Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers
Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease
Association of Rare <i>APOE</i> Missense Variants V236E and R251G With Risk of Alzheimer Disease
Genome-Wide Association Study of Alzheimer’s Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer’s Disease Multimodal Biomarker Discovery Dataset
Protective association of <i>HLA‐DRB1</i>*04 subtypes in neurodegenerative diseases implicates acetylated tau PHF6 sequences
Characteristics of subjective cognitive decline associated with amyloid positivity
TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer's disease biomarker levels
Pathophysiological subtypes of Alzheimer’s disease based on cerebrospinal fluid proteomics
Genome-wide association study of Alzheimer’s disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset
APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer’s disease
Inflammatory biomarkers in Alzheimer's disease plasma
A metabolite‐based machine learning approach to diagnose Alzheimer‐type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort
Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum
Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort
Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay
The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics
Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease
MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study
Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia
Prevalence of Cerebral Amyloid Pathology in Persons Without Dementia