Area of research
Molecular Biology · Immunology
Research interest
Research interests include Protein Degradation and Inhibitors, Ubiquitin and proteasome pathways, interferon and immune responses, and RNA Interference and Gene Delivery.
Targeted degradation of oncogenic KRASG12V triggers antitumor immunity in lung cancer models
Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells
TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma
Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules
Discovery of a selective inhibitor of doublecortin like kinase 1
Exploring Targeted Degradation Strategy for Oncogenic KRASG12C
A Mutation in Histone H2B Represents a New Class of Oncogenic Driver
The dTAG system for immediate and target-specific protein degradation
Mutant NPM1 Maintains the Leukemic State through HOX Expression
Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13
YY1 Is a Structural Regulator of Enhancer-Promoter Loops
Transcription control by the ENL YEATS domain in acute leukaemia
MELK is not necessary for the proliferation of basal-like breast cancer cells
A compendium of RNA-binding motifs for decoding gene regulation