Area of research
Cardiology and Cardiovascular Medicine · Genetics
Research interest
Research interests include Biology, Medicine, Genetics, Cardiology, Internal medicine, and Hypertrophic cardiomyopathy.
Evaluation of polygenic scores for hypertrophic cardiomyopathy in the general population and across clinical settings
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan
The Singapore National Precision Medicine Strategy
The penetrance of rare variants in cardiomyopathy-associated genes: A cross-sectional approach to estimating penetrance for secondary findings
A high-resolution map of human RNA translation
Analysis of clinically relevant variants from ancestrally diverse Asian genomes
Precision Phenotyping of Dilated Cardiomyopathy Using Multidimensional Data
Markers of Focal and Diffuse Nonischemic Myocardial Fibrosis Are Associated With Adverse Cardiac Remodeling and Prognosis in Patients With Hypertension: The REMODEL Study
Disease-specific variant pathogenicity prediction significantly improves variant interpretation in inherited cardiac conditions
Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models
Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in <i>TNNI3</i> and <i>TNNT2</i> That Are Common in Chinese Patients
Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis
Early Regenerative Capacity in the Porcine Heart
Beyond fitness tracking: The use of consumer-grade wearable data from normal volunteers in cardiovascular and lipidomics research
IL-11 is a crucial determinant of cardiovascular fibrosis
Utility of Post-Mortem Genetic Testing in Cases of Sudden Arrhythmic Death Syndrome
Titin-truncating variants affect heart function in disease cohorts and the general population
Defining the genetic architecture of hypertrophic cardiomyopathy: re-evaluating the role of non-sarcomeric genes
Development of a Comprehensive Sequencing Assay for Inherited Cardiac Condition Genes