Area of research
Oncology · Surgery
Research interest
Research interests include Pancreatic and Hepatic Oncology Research, Pancreatic function and diabetes, Cancer Genomics and Diagnostics, and Cancer Cells and Metastasis.
Abstract PR-11: Altered mRNA splicing mimics chromosome loss and drives pancreatic cancer
A pancreatic cancer organoid platform identifies an inhibitor specific to mutant KRAS
Ordered and deterministic cancer genome evolution after p53 loss.
A gene–environment-induced epigenetic program initiates tumorigenesis
A gene-environment-induced epigenetic program initiates tumorigenesis.
Uncertain Beginnings: Acinar and Ductal Cell Plasticity in the Development of Pancreatic Cancer
Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility
Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer
Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer.
ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity
Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer
α-Ketoglutarate links p53 to cell fate during tumour suppression
ID1 Mediates Escape from TGFβ Tumor Suppression in Pancreatic Cancer
Genomic Landscape of Pancreatic Adenocarcinoma in Younger versus Older Patients: Does Age Matter?
Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms
<i>EIF1AX</i> and <i>RAS</i> Mutations Cooperate to Drive Thyroid Tumorigenesis through ATF4 and c-MYC
Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer
Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing
Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype
Stratification of Pancreatic Ductal Adenocarcinoma: Combinatorial Genetic, Stromal, and Immunologic Markers
PanIN Neuroendocrine Cells Promote Tumorigenesis via Neuronal Cross-talk
Expression of Activated Ras in Gastric Chief Cells of Mice Leads to the Full Spectrum of Metaplastic Lineage Transitions
p53 mutations cooperate with oncogenic Kras to promote adenocarcinoma from pancreatic ductal cells
A draft map of the human proteome
Organoid Models of Human and Mouse Ductal Pancreatic Cancer
Oncogenic Kras Activates a Hematopoietic-to-Epithelial IL-17 Signaling Axis in Preinvasive Pancreatic Neoplasia
Zebrafish reporter lines reveal in vivo signaling pathway activities involved in pancreatic cancer
DCLK1 Marks a Morphologically Distinct Subpopulation of Cells With Stem Cell Properties in Preinvasive Pancreatic Cancer
Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells
Sympathetic Innervation during Development Is Necessary for Pancreatic Islet Architecture and Functional Maturation
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