Area of research
Radiology, Nuclear Medicine and Imaging · Cancer Research
Research interest
Research interests include Monoclonal and Polyclonal Antibodies Research, Protease and Inhibitor Mechanisms, Advanced biosensing and bioanalysis techniques, and Alzheimer's disease research and treatments.
Phagocytes as plaque catalysts: Human macrophages generate seeding-competent Aβ42 fibrils with cross-seeding activity
Lecanemab preferentially binds to smaller aggregates present at early Alzheimer's disease
Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein
The Alzheimer’s therapeutic Lecanemab attenuates Aβ pathology by inducing an amyloid-clearing program in microglia
Brain-penetrant complement inhibition mitigates neurodegeneration in an Alzheimer’s disease mouse model
LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons
Novel Human/Non-Human Primate Cross-Reactive Anti-Transferrin Receptor Nanobodies for Brain Delivery of Biologics
Anti‐mouse CD98hc nanobodies for brain delivery of a therapeutic moiety
VHHs as tools for therapeutic protein delivery to the central nervous system
AAV‐mediated delivery of an anti‐BACE1 VHH alleviates pathology in an Alzheimer's disease model
Identification and in vivo characterization of a brain-penetrating nanobody
Identification and characterization of Nanobodies targeting the EphA4 receptor