Area of research
Genetics · Molecular Biology
Research interest
Research interests include Glioma Diagnosis and Treatment, Ferroptosis and cancer prognosis, Single-cell and spatial transcriptomics, and Cancer Genomics and Diagnostics.
A brief history of ependymoma
Multidimensional profiling of heterogeneity in supratentorial ependymomas
Oncogene aberrations drive medulloblastoma progression, not initiation
Comparison of spatial transcriptomics technologies using tumor cryosections
Mapping naturally presented T cell antigens in medulloblastoma based on integrative multi-omics
Biglycan-driven risk stratification in ZFTA-RELA fusion supratentorial ependymomas through transcriptome profiling
Developing an advanced risk stratification model for pediatric intracranial ependymoma based on the prospective trial E-HIT2000 and subsequent registries
Author Correction: Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability
Developmental basis of SHH medulloblastoma heterogeneity
Comparison of spatial transcriptomics technologies using tumor cryosections
Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage
Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability
EPEN-14. MOLECULAR MARKERS AND PREDICTORS OF OUTCOME FOR PAEDIATRIC INTRACRANIAL EPENDYMOMA IN THE PROSPECTIVE, MULTICENTRE E-HIT2000 TRIAL AND SUBSEQUENT HIT-REGISTRIES: A POOLED ANALYSIS OF 244 PATIENTS
Author Correction: Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage
STEM-11. MULTIDIMENSIONAL PROFILING OF TUMOR CELL HETEROGENEITY REVEALS CELL-LINEAGE SPECIFIC FUNCTIONS IN SUPRATENTORIAL EPENDYMOMAS
Optimizing biomarkers for accurate ependymoma diagnosis, prognostication, and stratification within International Clinical Trials: A BIOMECA study
EPEN-10. SPINAL EPENDYMOMA WITH MYCN-AMPLIFICATION – A DISEASE OF CHILDHOOD AND YOUNG ADULTHOOD WITH DISMAL PROGNOSIS
The Current Landscape of Targeted Clinical Trials in Non-WNT/Non-SHH Medulloblastoma
Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage
Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion–Positive Supratentorial Ependymomas
Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors
Clinically aggressive pediatric spinal ependymoma with novel MYC amplification demonstrates molecular and histopathologic similarity to newly described MYCN-amplified spinal ependymomas
Single cell multi-omics analysis of chromothriptic medulloblastoma highlights genomic and transcriptomic consequences of genome instability
EPEN-03. ZFTA/C11ORF95 FUSIONS DRIVE SUPRATENTORIAL EPENDYMOMA VIA SHARED ONCOGENIC MECHANISMS
Abstract B71: Molecular heterogeneity and novel oncogenic fusions in <i>RELA-</i> and <i>YAP1-</i>negative supratentorial ependymoma
EPEN-18. CROSS-SPECIES GENOMICS IDENTIFIES <i>GLI2</i> AS AN ONCOGENE OF <i>C11orf95</i> FUSION-POSITIVE SUPRATENTORIAL EPENDYMOMA
MYCN amplification drives an aggressive form of spinal ependymoma
Transcriptional profiling of medulloblastoma with extensive nodularity (MBEN) reveals two clinically relevant tumor subsets with VSNL1 as potent prognostic marker