Area of research
Molecular Biology · Genetics
Research interest
Research interests include Genomics and Chromatin Dynamics, Single-cell and spatial transcriptomics, Glioma Diagnosis and Treatment, and RNA Research and Splicing.
Oncogene aberrations drive medulloblastoma progression, not initiation
Comparison of spatial transcriptomics technologies using tumor cryosections
Two distinct chromatin modules regulate proinflammatory gene expression
Comparison of spatial transcriptomics technologies using tumor cryosections
Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage
Two distinct chromatin modules regulate proinflammatory gene expression
Cell-state plasticity drives heterogeneity in Group 3/4 medulloblastoma
Author Correction: Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage
Medulloblastoma oncogene aberrations are not involved in tumor initiation, but essential for disease progression and therapy resistance
Transcription activation is enhanced by multivalent interactions independent of phase separation
DNA sequence-dependent formation of heterochromatin nanodomains
ALT-FISH quantifies alternative lengthening of telomeres activity by imaging of single-stranded repeats
Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage
Assessing the Phase Separation Propensity of Proteins in Living Cells Through Optodroplet Formation
Transcription activation is enhanced by multivalent interactions independent of phase separation
Mouse Heterochromatin Adopts Digital Compaction States without Showing Hallmarks of HP1-Driven Liquid-Liquid Phase Separation
DNA sequence-dependent formation of heterochromatin nanodomains
Tracing Reversible Light-Induced Chromatin Binding with Near-infrared Fluorescent Proteins
Light-Induced Transcription Activation for Time-Lapse Microscopy Experiments in Living Cells
Real-time observation of light-controlled transcription in living cells
Real-time observation of light-controlled transcription in living cells
Specificity, propagation, and memory of pericentric heterochromatin