Area of research
Physiology · Neurology
Research interest
Research interests include Cell biology, Chemistry, CREB, Neuroscience, Neurodegeneration, and Hyperphosphorylation.
Targeting tau in Alzheimer's disease: from mechanisms to clinical therapy
A novel small-molecule PROTAC selectively promotes tau clearance to improve cognitive functions in Alzheimer-like models
Medial septum tau accumulation induces spatial memory deficit via disrupting medial septum–hippocampus cholinergic pathway
Periphery Biomarkers for Objective Diagnosis of Cognitive Decline in Type 2 Diabetes Patients
Peripheral inflammation promotes brain tau transmission via disrupting blood–brain barrier
Tau acetylates and stabilizes β‐catenin thereby promoting cell survival
Tau‐induced upregulation of C/EBPβ‐TRPC1‐SOCE signaling aggravates tauopathies: A vicious cycle in Alzheimer neurodegeneration
Tau accumulation triggers STAT1‐dependent memory deficits by suppressing NMDA receptor expression
Tau inhibits PKA by nuclear proteasome‐dependent PKAR2α elevation with suppressed CREB/GluA1 phosphorylation
Co-Expression of Three Wild-Type 3R-Tau Isoforms Induces Memory Deficit via Oxidation-Related DNA Damage and Cell Death: A Promising Model for Tauopathies
TRPC1 Null Exacerbates Memory Deficit and Apoptosis Induced by Amyloid-β
Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signaling
Accumulation of human full-length tau induces degradation of nicotinic acetylcholine receptor α4 via activating calpain-2