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Can Wei

Hospital for Sick Children · CA
Area of research
Molecular Biology · Pathology and Forensic Medicine
Research interest
Research interests include Internal medicine, Chemistry, Spermine, Endocrinology, Cardioprotection, and Diabetic cardiomyopathy.
h-index
citations
1,143
works
43
NIH funding
primary concept
email

Recent publications

The Effects of Polyphenols on Doxorubicin‐Induced Nephrotoxicity by Modulating Inflammatory Cytokines, Apoptosis, Oxidative Stress, and Oxidative <scp>DNA</scp> Damage
Phytotherapy Research 2025cited by 12position: middledoi
Associations of dietary inflammatory index and composite dietary antioxidant index with erectile dysfunction and the mediating role of metabolic dysregulation: a cross-sectional analysis of NHANES 2001–2004 data
Frontiers in Nutrition 2025cited by 2position: middledoi
The potential mechanisms of reciprocal regulation of gut microbiota-liver immune signaling in metabolic dysfunction-associated steatohepatitis revealed in multi-omics analysis
mSystems 2025cited by 1position: lastdoi
SIRT5-related lysine demalonylation of GSTP1 contributes to cardiomyocyte pyroptosis suppression in diabetic cardiomyopathy
International Journal of Biological Sciences 2024cited by 42position: firstdoi
Multi-omics mechanical analysis of gut microbiota, carboxylic acids, and cardiac gene expression interaction triggering diabetic cardiomyopathy
mSystems 2024cited by 5position: lastdoi
Paeoniflorin alleviates AngII-induced cardiac hypertrophy in H9c2 cells by regulating oxidative stress and Nrf2 signaling pathway
Biomedicine & Pharmacotherapy 2023cited by 69position: middledoi
Gut microbial dysbiosis is associated with metabolism and immune factors in liver fibrosis mice
International Journal of Biological Macromolecules 2023cited by 14position: lastdoi
Exogenous Spermidine Alleviates Diabetic Myocardial Fibrosis Via Suppressing Inflammation and Pyroptosis in db/db Mice
Balkan Medical Journal 2023cited by 13position: firstdoi
Long‐term safety of ultrathin bioabsorbable‐polymer sirolimus‐eluting stents versus thin durable‐polymer drug‐eluting stents in acute coronary syndrome: A systematic review and meta‐analysis
Clinical Cardiology 2023cited by 13position: middledoi
Exogenous hydrogen sulfide inhibits the senescence of cardiomyocytes through modulating mitophagy in rats
Cellular Signalling 2022cited by 17position: middledoi
Transcriptomics Coupled to Proteomics Reveals Novel Targets for the Protective Role of Spermine in Diabetic Cardiomyopathy
Oxidative Medicine and Cellular Longevity 2022cited by 11position: firstdoi
Spermine Regulates Immune and Signal Transduction Dysfunction in Diabetic Cardiomyopathy
Frontiers in Endocrinology 2022cited by 11position: firstdoi
[Retracted] Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose‐Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR‐182‐5p/TRIB3 Axis
Oxidative Medicine and Cellular Longevity 2022cited by 11position: middledoi
Dopamine 1 receptors inhibit apoptosis via activating CSE/H<sub>2</sub>S pathway in high glucose‐induced vascular endothelial cells
Cell Biology International 2022cited by 9position: middledoi
SKF38393 prevents high glucose (HG)-induced endothelial dysfunction by inhibiting the effects of HG on cystathionine γ-lyase/hydrogen sulfide activity and via a RhoA/ROCK1 pathway
Frontiers in Bioscience-Landmark 2022cited by 7position: middledoi
Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway
International Journal of Molecular Medicine 2021cited by 34position: lastdoi
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor
Redox Biology 2020cited by 65position: lastdoi
Exogenous spermine attenuates myocardial fibrosis in diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress and the canonical Wnt signaling pathway
Cell Biology International 2020cited by 50position: lastdoi
Spermine Protects Cardiomyocytes from High Glucose-Induced Energy Disturbance by Targeting the CaSR-gp78-Ubiquitin Proteasome System
Cardiovascular Drugs and Therapy 2020cited by 26position: lastdoi
Dopamine 1 receptor activation protects mouse diabetic podocytes injury via regulating the PKA/NOX-5/p38 MAPK axis
Experimental Cell Research 2020cited by 25position: lastdoi
Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF‐β1/Smads and NFκB pathways
Clinical and Experimental Pharmacology and Physiology 2020cited by 24position: lastdoi
Correction: Calcium sensing receptor protects high glucose-induced energy metabolism disorder via blocking gp78-ubiquitin proteasome pathway
Cell Death and Disease 2020cited by 1position: middledoi
[Spermine attenuates high glucose-induced myocardial fibrosis by regulating the cell cycle].
PubMed 2020cited by 1position: lastdoi
[The role of CaSR expression in diabetic cirrhosis injury and fibrosis in rats].
PubMed 2020cited by 0position: lastdoi
H2S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling
Aging 2019cited by 26position: middledoi
Calcium‑sensing receptor promotes high glucose‑induced myocardial fibrosis via upregulation of the TGF‑β1/Smads pathway in cardiac fibroblasts
Molecular Medicine Reports 2019cited by 26position: lastdoi
NPS2390, a selective calcium-sensing receptor antagonist controls the phenotypic modulation of hypoxic human pulmonary arterial smooth muscle cells by regulating autophagy
Journal of Translational Internal Medicine 2019cited by 23position: middledoi
[Exogenous spermine alleviates myocardial injury induced by hyperglycemia by inhibiting golgi stress].
PubMed 2019cited by 4position: lastdoi
Inhibition of HMGB1 mediates neuroprotection of traumatic brain injury by modulating the microglia/macrophage polarization
Biochemical and Biophysical Research Communications 2018cited by 67position: middledoi
THE ROLE OF CALCIUM SENSING RECEPTOR IN DIABETIC CARDIOMYOPATHY AND ITS UNDERLAYING MECHANISM
Pathophysiology 2018cited by 0position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Changqing Xu · Shandong University23 papers (2014–2021)Hongzhu Li · Harbin Medical University19 papers (2014–2022)Yuehong Wang · University of Illinois Chicago12 papers (2015–2020)Bing Zhao · South China Agricultural University7 papers (2019–2024)Shuzhi Bai · Harbin Medical University7 papers (2014–2022)Jing Hu · Wuhan University6 papers (2019–2020)Yajun Zhao · Fudan University6 papers (2014–2020)Yuxin Xi · Harbin Medical University6 papers (2017–2022)Rui Wang · Wuhan Ship Development & Design Institute6 papers (2014–2020)Xin Wen · Harbin Medical University6 papers (2017–2022)Lingyun Wu · Harbin Medical University6 papers (2014–2020)Hong-Jiang Shao · Harbin Medical University5 papers (2015–2016)Siwei Li · Harbin Medical University5 papers (2020–2021)Yuehong Wang · University of Illinois Chicago5 papers (2017–2020)Junting Chen · Guangdong Medical College5 papers (2020–2021)Xiaoting Shao · Harbin Medical University5 papers (2019–2020)Hongxia Li · University of Kentucky4 papers (2015–2022)Xue Peng · Guiyang Medical University4 papers (2015–2018) · 4 papers (2018–2024)Jinghui Hao · Harbin Medical University3 papers (2022–2022)