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Lingyun Wu

Harbin Medical University · CN
Area of research
Biochemistry · Clinical Biochemistry
Research interest
Research focused on Cardioprotection and Mitochondrion, with related work in Protein kinase B, Sodium hydrosulfide, Calcium-sensing receptor. Notable publications include 'Hydrogen sulfide (H 2 S) metabolism in mitochondria and its regulatory role in energy production', 'Oxygen-sensitive mitochondrial accumulation of cystathionine β-synthase mediated by Lon protease', and 'Involvement of exogenous H2S in recovery of cardioprotection from ischemic post-conditioning via increase of autophagy in the aged hearts'.
h-index
citations
1,417
works
27
NIH funding
primary concept
email

Recent publications

Localized delivery and retention of hydrogen sulfide causing regional lipid accumulation in mouse adipose tissues in vivo
Communications Biology 2025cited by 2position: middledoi
Deficiency of cystathionine gamma-lyase promotes aortic elastolysis and medial degeneration in aged mice
Journal of Molecular and Cellular Cardiology 2022cited by 24position: middledoi
Hydrogen Sulfide Promotes Adipocyte Differentiation, Hyperplasia, and Hypertrophy
Engineering 2022cited by 7position: middledoi
Cystathionine gamma‐lyase/H <sub>2</sub> S signaling facilitates myogenesis under aging and injury condition
The FASEB Journal 2021cited by 19position: middledoi
Effect of hydrogen sulfide on glycolysis‐based energy production in mouse erythrocytes
Journal of Cellular Physiology 2021cited by 9position: middledoi
Interaction among estrogen, IGF-1, and H2S on smooth muscle cell proliferation
Journal of Endocrinology 2020cited by 20position: middledoi
H<sub>2</sub>S-stimulated bioenergetics in chicken erythrocytes and the underlying mechanism
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2020cited by 18position: middledoi
Correction: Calcium sensing receptor protects high glucose-induced energy metabolism disorder via blocking gp78-ubiquitin proteasome pathway
Cell Death and Disease 2020cited by 1position: middledoi
EXOGENOUS H2S CONTRIBUTES TO RECOVERY OF ISCHEMIC POST-CONDITIONING-INDUCED CARDIOPROTECTION VIA INCREASE OF AUTOPHAGY IN THE AGED HEARTS
Pathophysiology 2018cited by 0position: lastdoi
Calcium sensing receptor protects high glucose-induced energy metabolism disorder via blocking gp78-ubiquitin proteasome pathway
Cell Death and Disease 2017cited by 38position: middledoi
Exogenous H2S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes
Cell & Bioscience 2017cited by 23position: middledoi
Involvement of exogenous H2S in recovery of cardioprotection from ischemic post-conditioning via increase of autophagy in the aged hearts
International Journal of Cardiology 2016cited by 77position: middledoi
Exogenous H2S contributes to recovery of ischemic post-conditioning-induced cardioprotection by decrease of ROS level via down-regulation of NF-κB and JAK2-STAT3 pathways in the aging cardiomyocytes
Cell & Bioscience 2016cited by 53position: middledoi
The interaction of estrogen and CSE/H<sub>2</sub>S pathway in the development of atherosclerosis
American Journal of Physiology-Heart and Circulatory Physiology 2016cited by 51position: middledoi
Mediation of exogenous hydrogen sulfide in recovery of ischemic post-conditioning-induced cardioprotection via down-regulating oxidative stress and up-regulating PI3K/Akt/GSK-3β pathway in isolated aging rat hearts
Cell & Bioscience 2015cited by 58position: middledoi
Exogenous hydrogen sulfide restores cardioprotection of ischemic post-conditioning via inhibition of mPTP opening in the aging cardiomyocytes
Cell & Bioscience 2015cited by 39position: middledoi
Interaction of H<sub><b>2</b></sub>S with Calcium Permeable Channels and Transporters
Oxidative Medicine and Cellular Longevity 2015cited by 32position: middledoi
Exogenous spermine inhibits the proliferation of human pulmonary artery smooth muscle cells caused by chemically-induced hypoxia via the suppression of the ERK1/2- and PI3K/AKT-associated pathways
International Journal of Molecular Medicine 2015cited by 28position: middledoi
Involvement of calcium-sensing receptors in hypoxia-induced vascular remodeling and pulmonary hypertension by promoting phenotypic modulation of small pulmonary arteries
Molecular and Cellular Biochemistry 2014cited by 41position: middledoi
Mediation of dopamine D2 receptors activation in post-conditioning-attenuated cardiomyocyte apoptosis
Experimental Cell Research 2014cited by 29position: middledoi
Oxygen-sensitive mitochondrial accumulation of cystathionine β-synthase mediated by Lon protease
Proceedings of the National Academy of Sciences 2013cited by 204position: middledoi
Involvement of dopamine D2 receptors activation in ischemic post-conditioning-induced cardioprotection through promoting PKC-ε particulate translocation in isolated rat hearts
Molecular and Cellular Biochemistry 2013cited by 20position: middledoi
The expression of calcium-sensing receptor in mouse embryonic stem cells (mESCs) and its influence on differentiation of mESC into cardiomyocytes
Differentiation 2013cited by 11position: middledoi
Hydrogen sulfide (H <sub>2</sub> S) metabolism in mitochondria and its regulatory role in energy production
Proceedings of the National Academy of Sciences 2012cited by 466position: middledoi
Hydrogen sulfide inhibits the translational expression of hypoxia‐inducible factor‐1α
British Journal of Pharmacology 2012cited by 74position: middledoi
Interaction of Hydrogen Sulfide and Estrogen on the Proliferation of Vascular Smooth Muscle Cells
PLoS ONE 2012cited by 37position: middledoi
Exogenous hydrogen sulfide attenuates diabetic myocardial injury through cardiac mitochondrial protection
Molecular and Cellular Biochemistry 2012cited by 36position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Rui Wang · Wuhan Ship Development & Design Institute27 papers (2012–2025)Hongzhu Li · Harbin Medical University16 papers (2012–2022)Changqing Xu · Shandong University13 papers (2012–2018)Guangdong Yang · Harbin Medical University11 papers (2012–2020)Shuzhi Bai · Harbin Medical University10 papers (2013–2018)Bo Wu · Palo Alto University7 papers (2012–2017)Weihua Zhang · Harbin Medical University7 papers (2012–2020) · 6 papers (2016–2025)Yuehong Wang · University of Illinois Chicago6 papers (2015–2018)Can Wei · Hospital for Sick Children6 papers (2014–2020)Hongxia Li · University of Kentucky5 papers (2013–2016)Yajun Zhao · Fudan University5 papers (2012–2020)Ming Fu · Huazhong Agricultural University5 papers (2012–2021)Weiming Sun · Nanchang University5 papers (2015–2018)Lina Li · Ministry of Education of the People's Republic of China4 papers (2015–2018)Yuehong Wang · University of Illinois Chicago4 papers (2017–2022)Tian Shuang · Shanghai Jiao Tong University3 papers (2016–2020)Ye Tian · Harbin Medical University3 papers (2013–2020)Huajian Teng · University of Cape Town2 papers (2012–2013)Zhuping Jin · Ministry of Education of the People's Republic of China2 papers (2020–2021)