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Fabricio Loayza‐Puch

German Cancer Research Center · DE
Area of research
Molecular Biology · Oncology
Research interest
Research interests include RNA modifications and cancer, RNA and protein synthesis mechanisms, Peptidase Inhibition and Analysis, and Cancer-related molecular mechanisms research.
h-index
19
citations
2,358
works
48
NIH funding
primary concept
email

Recent publications

The <scp>m6A</scp> demethylase <scp>FTO</scp> promotes C/ <scp>EBPβ</scp> ‐ <scp>LIP</scp> translation to perform oncogenic functions in breast cancer cells
FEBS Journal 2025cited by 5position: middledoi
Upstream open reading frame translation enhances immunogenic peptide presentation in mitotically arrested cancer cells
Nature Communications 2025cited by 3position: lastdoi
mTORC1 cooperates with tRNA wobble modification to sustain the protein synthesis machinery
Nature Communications 2025cited by 2position: middledoi
Dual Ribosome Profiling reveals metabolic limitations of cancer and stromal cells in the tumor microenvironment
Nature Communications 2025cited by 1position: lastdoi
Upstream open reading frame translation enhances immunogenic peptide presentation in mitotically arrested cancer cells
bioRxiv (Cold Spring Harbor Laboratory) 2025cited by 1position: lastdoi
P53-dependent hypusination of eIF5A affects mitochondrial translation and senescence immune surveillance
Nature Communications 2024cited by 15position: lastdoi
Identifying colorectal cancer-specific vulnerabilities in the Wnt-driven long non-coding transcriptome
Gut 2024cited by 5position: middledoi
Gene and protein sequence features augment HLA class I ligand predictions
Cell Reports 2024cited by 4position: middledoi
DNMT and HDAC inhibition induces immunogenic neoantigens from human endogenous retroviral element-derived transcripts
Nature Communications 2023cited by 85position: middledoi
The MTORC1-AHR pathway sustains translation and autophagy in tumours under tryptophan stress
bioRxiv (Cold Spring Harbor Laboratory) 2023cited by 4position: middledoi
Breast Cancer Metastatic Progression Requires mRNA Posttranscriptional Suppression
Cancer Research 2023cited by 1position: lastdoi
Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
Nature Metabolism 2022cited by 148position: middledoi
Roles of eIF5A in the immunosurveillance of cellular senescence
Cancer Biology and Medicine 2022cited by 5position: middledoi
Author Correction: Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
Nature Metabolism 2022cited by 4position: middledoi
PYCR1-dependent proline synthesis in cancer-associated fibroblasts is required for the deposition of pro-tumorigenic extracellular matrix
bioRxiv (Cold Spring Harbor Laboratory) 2020cited by 3position: middledoi
Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells
Nature Communications 2019cited by 105position: middledoi
A fragment-like approach to PYCR1 inhibition
Bioorganic & Medicinal Chemistry Letters 2019cited by 39position: middledoi
Myc coordinates transcription and translation to enhance transformation and suppress invasiveness
EMBO Reports 2015cited by 60position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Reuven Agami · University of Michigan–Ann Arbor6 papers (2015–2025)Alexander Kowar · German Cancer Research Center5 papers (2024–2025)Ekaterina Stepanova · German Cancer Research Center5 papers (2020–2025)Rossella Del Pizzo · German Cancer Research Center4 papers (2024–2025)Cinthia Claudia Amaya Ramirez · German Cancer Research Center3 papers (2023–2025)Jeroen Krijgsveld · Medical Research Council3 papers (2023–2025)Wilhelm Palm · Heidelberg University3 papers (2024–2025) · 2 papers (2025–2025)Jonas P. Becker · German Cancer Research Center2 papers (2025–2025) · 2 papers (2025–2025) · 2 papers (2019–2020)Celia R. Berkers · Utrecht University2 papers (2019–2024)Ali Hyder Baig · German Cancer Research Center2 papers (2024–2025)Esther A. Zaal · Utrecht University2 papers (2019–2024)Angelika B. Riemer · German Cancer Research Center2 papers (2025–2025)Xiangli Jiang · Tianjin Medical University Cancer Institute and Hospital2 papers (2022–2024)Daniela Aviles-Huerta · German Cancer Research Center2 papers (2024–2025)Fiona Megan Tilghman · German Cancer Research Center2 papers (2025–2025)Hanan Sakeer · German Cancer Research Center2 papers (2025–2025)Toman Borteçen · German Cancer Research Center2 papers (2024–2025)