Area of research
Cellular and Molecular Neuroscience · Materials Chemistry
Research interest
Research interests include Neuroscience and Neuropharmacology Research, Receptor Mechanisms and Signaling, Crystallization and Solubility Studies, and X-ray Diffraction in Crystallography.
Structure and organization of AMPA receptor-TARP complexes in the mammalian cerebellum.
Dopamine increases protein synthesis in hippocampal neurons enabling dopamine-dependent LTP
Architecture, dynamics and biogenesis of GluA3 AMPA glutamate receptors.
Tuning synaptic strength by regulation of AMPA glutamate receptor localization.
Proton-triggered rearrangement of the AMPA receptor N-terminal domains impacts receptor kinetics and synaptic localization.
Regulating calcium flux through AMPA glutamate receptors.
‘Mini analysis’ is an unreliable reporter of synaptic changes
Dopamine increases protein synthesis in hippocampal neurons enabling dopamine-dependent LTP
A Small Interfering Peptide Potentiates AMPA Receptor Diffusional Trapping and Prevents Social-Isolation-Induced Forgetting of Fear Memory
Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Modulatory mechanisms of TARP γ8-selective AMPA receptor therapeutics.
Mechanisms underlying TARP modulation of the GluA1/2-γ8 AMPA receptor.
Modulatory mechanisms of TARP γ8-selective AMPA receptor therapeutics
Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels
Gating and modulation of a hetero-octameric AMPA glutamate receptor.
AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions.
Characterizing the binding and function of TARP γ8-selective AMPA receptor modulators.
An inhalation anaesthesia approach for neonatal mice allowing streamlined stereotactic injection in the brain
Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP γ8.
Mechanisms of postsynaptic localization of AMPA-type glutamate receptors and their regulation during long-term potentiation.
Structural biology of glutamate receptor ion channels: towards an understanding of mechanism.
Druggability Simulations and X-Ray Crystallography Reveal a Ligand-Binding Site in the GluA3 AMPA Receptor N-Terminal Domain.
Activation and desensitization of ionotropic glutamate receptors by selectively triggering pre-existing motions.
Factors influencing success of clinical genome sequencing across a broad spectrum of disorders
Differences in AMPA and Kainate Receptor Interactomes Facilitate Identification of AMPA Receptor Auxiliary Subunit GSG1L