Area of research
Molecular Biology · Infectious Diseases
Research interest
Research interests include Biology, Biochemistry, Ubiquitin, Chemistry, Mycobacterium tuberculosis, and Ubiquitin ligase.
GPR68 Senses Flow and Is Essential for Vascular Physiology
Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M
System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes
Discovery of a PCAF Bromodomain Chemical Probe
Aldehyde Dehydrogenase Is Regulated by β-Catenin/TCF and Promotes Radioresistance in Prostate Cancer Progenitor Cells
Direct inhibitors of InhA are active against <i>Mycobacterium tuberculosis</i>
Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease
KAF156 Is an Antimalarial Clinical Candidate with Potential for Use in Prophylaxis, Treatment, and Prevention of Disease Transmission
Male-Specific Fruitless Isoforms Target Neurodevelopmental Genes to Specify a Sexually Dimorphic Nervous System
Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis
A Strategy for Modulation of Enzymes in the Ubiquitin System
Mitotic Evolution of Plasmodium falciparum Shows a Stable Core Genome but Recombination in Antigen Families
Antituberculosis thiophenes define a requirement for Pks13 in mycolic acid biosynthesis
Rasgrp1 mutation increases naïve T-cell CD44 expression and drives mTOR-dependent accumulation of Helios+ T cells and autoantibodies
SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis
A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen
Two ZnF-UBP Domains in Isopeptidase T (USP5)