Area of research
Immunology · Virology
Research interest
Research interests include HIV Research and Treatment, Immune Cell Function and Interaction, Immunotherapy and Immune Responses, and T-cell and B-cell Immunology.
Identifying correlates of viral rebound timing and viral control in SHIV-infected infant macaques after ART interruption
Vaccination induces broadly neutralizing antibody precursors to HIV gp41
TREM2+ and interstitial-like macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques
Efficacy of mRNA-1273 and Novavax ancestral or BA.1 spike booster vaccines against SARS-CoV-2 BA.5 infection in nonhuman primates
Intradermal but not intramuscular modified vaccinia Ankara immunizations protect against intravaginal tier2 simian-human immunodeficiency virus challenges in female macaques
Defining the risk of SARS-CoV-2 variants on immune protection
A modified vaccinia Ankara vaccine expressing spike and nucleocapsid protects rhesus macaques against SARS-CoV-2 Delta infection
Lymph node CXCR5+ NK cells associate with control of chronic SHIV infection
PD-1 blockade following ART interruption enhances control of pathogenic SIV in rhesus macaques
Challenges and Opportunities of Therapies Targeting Early Life Immunity for Pediatric HIV Cure
SARS-CoV-2 RBD trimer protein adjuvanted with Alum-3M-052 protects from SARS-CoV-2 infection and immune pathology in the lung
A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs
Cutting Edge: Mouse SARS-CoV-2 Epitope Reveals Infection and Vaccine-Elicited CD8 T Cell Responses
PD-1 blockade and vaccination provide therapeutic benefit against SIV by inducing broad and functional CD8 <sup>+</sup> T cells in lymphoid tissue
The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection
T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers
HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge
Vaccine induction of antibodies and tissue-resident CD8+ T cells enhances protection against mucosal SHIV-infection in young macaques
Impact of T <sub>h</sub> 1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques
Combination anti–PD-1 and antiretroviral therapy provides therapeutic benefit against SIV
Tfh1 Cells in Germinal Centers During Chronic HIV/SIV Infection
Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection
Oral microbiome in HIV-associated periodontitis
A Trimeric HIV-1 Envelope gp120 Immunogen Induces Potent and Broad Anti-V1V2 Loop Antibodies against HIV-1 in Rabbits and Rhesus Macaques
Immunogenicity and efficacy of DNA/MVA HIV vaccines in rhesus macaque models
The rectal mucosa and condomless receptive anal intercourse in HIV-negative MSM: implications for HIV transmission and prevention
Induction of Th1-Biased T Follicular Helper (Tfh) Cells in Lymphoid Tissues during Chronic Simian Immunodeficiency Virus Infection Defines Functionally Distinct Germinal Center Tfh Cells
Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5α Restrictive Macaques
Virus-Like Particles Displaying Trimeric Simian Immunodeficiency Virus (SIV) Envelope gp160 Enhance the Breadth of DNA/Modified Vaccinia Virus Ankara SIV Vaccine-Induced Antibody Responses in Rhesus Macaques
Decreased T Follicular Regulatory Cell/T Follicular Helper Cell (TFH) in Simian Immunodeficiency Virus–Infected Rhesus Macaques May Contribute to Accumulation of TFH in Chronic Infection