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Guido Silvestri

International AIDS Vaccine Initiative ·
Area of research
Virology · Immunology
Research interest
Research interests include HIV Research and Treatment, Immune Cell Function and Interaction, T-cell and B-cell Immunology, and Cytomegalovirus and herpesvirus research.
h-index
82
citations
27,226
works
416
NIH funding
primary concept
email

Recent publications

Immune-mediated strategies to solving the HIV reservoir problem
Nature reviews. Immunology 2025cited by 12position: lastdoi
Diverse priming outcomes under conditions of very rare precursor B cells
Immunity 2025cited by 12position: middledoi
Vaccination with an mRNA-encoded membrane-bound HIV envelope trimer induces neutralizing antibodies in animal models
Science Translational Medicine 2025cited by 12position: middledoi
HIV broadly neutralizing antibody precursors to the Apex epitope induced in nonhuman primates
Science Immunology 2025cited by 8position: middledoi
Highly functional and prolonged germinal center T follicular helper cell responses are associated with enhanced neutralizing antibody development
Immunity 2025cited by 6position: middledoi
Vaccination of nonhuman primates elicits a broadly neutralizing antibody lineage targeting a quaternary epitope on the HIV-1 Env trimer
Immunity 2025cited by 4position: middledoi
Identifying correlates of viral rebound timing and viral control in SHIV-infected infant macaques after ART interruption
Science Translational Medicine 2025cited by 2position: middledoi
Vaccination induces broadly neutralizing antibody precursors to HIV gp41
Nature Immunology 2024cited by 50position: middledoi
The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression
Cell 2024cited by 46position: middledoi
Distinct SIV-specific CD8+ T cells in the lymph node exhibit simultaneous effector and stem-like profiles and are associated with limited SIV persistence
Nature Immunology 2024cited by 29position: middledoi
Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption
Nature Immunology 2024cited by 22position: middledoi
Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection
Nature Communications 2023cited by 86position: middledoi
AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques
Nature Medicine 2023cited by 46position: middledoi
Human T cells efficiently control RSV infection
JCI Insight 2023cited by 40position: middledoi
CD8+ T cells promote HIV latency by remodeling CD4+ T cell metabolism to enhance their survival, quiescence, and stemness
Immunity 2023cited by 39position: middledoi
Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19
Nature Communications 2023cited by 32position: middledoi
Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques
Science Immunology 2023cited by 28position: middledoi
A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates
Nature Communications 2023cited by 24position: middledoi
Author Correction: Long-primed germinal centres with enduring affinity maturation and clonal migration
Nature 2023cited by 16position: middledoi
Long-primed germinal centres with enduring affinity maturation and clonal migration
Nature 2022cited by 188position: middledoi
From structure to sequence: Antibody discovery using cryoEM
Science Advances 2022cited by 49position: middledoi
Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy
DOAJ (DOAJ: Directory of Open Access Journals) 2022cited by 41position: middle
Limited induction of SARS-CoV-2–specific T cell responses in children with multisystem inflammatory syndrome compared with COVID-19
JCI Insight 2022cited by 24position: middledoi
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity
Science Immunology 2021cited by 167position: middledoi
Histopathological findings and clinicopathologic correlation in COVID-19: a systematic review
Modern Pathology 2021cited by 118position: middledoi
The Longest Persistence of Viable SARS-CoV-2 With Recurrence of Viremia and Relapsing Symptomatic COVID-19 in an Immunocompromised Patient—A Case Study
Open Forum Infectious Diseases 2021cited by 94position: middledoi
Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM
Nature Communications 2021cited by 79position: middledoi
IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques
Nature Communications 2021cited by 40position: middledoi
Combined PET and whole-tissue imaging of lymphatic-targeting vaccines in non-human primates
Biomaterials 2021cited by 39position: middledoi
Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2
Science Advances 2021cited by 36position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Mirko Paiardini · Emory Healthcare28 papers (2012–2025)Steven E. Bosinger · Emory University23 papers (2012–2024)Ann Chahroudi · Emory University19 papers (2012–2022)Thomas H. Vanderford · Emory and Henry College16 papers (2012–2021)Diane G. Carnathan · Emory University15 papers (2012–2025)Jacob D. Estes · MIT University11 papers (2012–2019)Luca Micci · Merck & Co., Inc., Rahway, NJ, USA (United States)10 papers (2012–2021)Shane Crotty · La Jolla Institute for Immunology9 papers (2012–2025)Benton Lawson · Atlanta VA Medical Center9 papers (2012–2018)Maud Mavigner · Emory University8 papers (2014–2021)Jeffrey D. Lifson · Center for Cancer Research8 papers (2012–2021)Kirk A. Easley · Emory University8 papers (2013–2021)Cynthia A. Derdeyn · University of Washington7 papers (2012–2016)François Villinger · The University of Texas MD Anderson Cancer Center7 papers (2012–2021)William R. Schief · Scripps Research Institute6 papers (2012–2025)Colleen S. McGary · Theratechnologies (Canada)6 papers (2013–2018)Jason M. Brenchley · University of Cape Town6 papers (2012–2015)Barbara Cervasi · Emory University5 papers (2012–2019) · 5 papers (2014–2019)Rama Rao Amara · Emory Healthcare5 papers (2012–2015)