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Jeffrey D. Lifson

Center for Cancer Research · US
🔎 Find collaborators in Virology · Immunology →
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Area of research
Virology · Immunology
Research interest
Research interests include Virology, Biology, Simian immunodeficiency virus, Immunology, Immune system, and Human immunodeficiency virus (HIV).
h-index
citations
7,597
works
62
NIH funding
primary concept
email

Recent publications

Determinants of successful AAV-vectored delivery of HIV-1 bNAbs in early life
Nature 2025cited by 10position: middledoi
Origin and Correlates of Viral Rebound in SIV-Infected Rhesus Macaques Following ART Discontinuation
bioRxiv (Cold Spring Harbor Laboratory) 2025cited by 2position: middledoi
Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption
Nature Immunology 2024cited by 22position: middledoi
Acute-phase innate immune responses in SIVmac239-infected Mamu-B*08+ Indian rhesus macaques may contribute to the establishment of elite control
Frontiers in Immunology 2024cited by 4position: middledoi
AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques
Nature Medicine 2023cited by 46position: middledoi
Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy
Science Translational Medicine 2022cited by 101position: middledoi
Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus
Nature Communications 2022cited by 10position: middledoi
IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques
Nature Communications 2021cited by 40position: middledoi
CD8 Lymphocyte Depletion Enhances the Latency Reversal Activity of the SMAC Mimetic AZD5582 in ART-Suppressed Simian Immunodeficiency Virus-Infected Rhesus Macaques
Journal of Virology 2021cited by 28position: middledoi
Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo
Nature 2020cited by 317position: middledoi
Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells
Nature 2020cited by 194position: middledoi
CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption
Nature Medicine 2020cited by 105position: middledoi
Long-Term Delivery of an Anti-SIV Monoclonal Antibody With AAV
Frontiers in Immunology 2020cited by 47position: middledoi
SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques
Journal of Virology 2020cited by 37position: middledoi
Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells
Nature 2020cited by 28position: middledoi
Rectal Acquisition of Simian Immunodeficiency Virus (SIV) SIVmac239 Infection despite Vaccine-Induced Immune Responses against the Entire SIV Proteome
Journal of Virology 2020cited by 10position: middledoi
Adeno-Associated Virus Delivery of Anti-HIV Monoclonal Antibodies Can Drive Long-Term Virologic Suppression
Immunity 2019cited by 128position: middledoi
The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections
Cell Host & Microbe 2019cited by 102position: middledoi
Anti-drug Antibody Responses Impair Prophylaxis Mediated by AAV-Delivered HIV-1 Broadly Neutralizing Antibodies
Molecular Therapy 2019cited by 58position: middledoi
Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes
PLoS Pathogens 2019cited by 27position: middledoi
Derivation of simian tropic HIV-1 infectious clone reveals virus adaptation to a new host
Proceedings of the National Academy of Sciences 2019cited by 17position: middledoi
Vaccine protection against SIVmac239 acquisition
Proceedings of the National Academy of Sciences 2019cited by 16position: middledoi
Elevated <i>HLA-A</i> expression impairs HIV control through inhibition of NKG2A-expressing cells
Science 2018cited by 152position: middledoi
Site-Specific Glycosylation of Virion-Derived HIV-1 Env Is Mimicked by a Soluble Trimeric Immunogen
Cell Reports 2018cited by 147position: middledoi
Sex-Based Differences in Human Immunodeficiency Virus Type 1 Reservoir Activity and Residual Immune Activation
The Journal of Infectious Diseases 2018cited by 95position: middledoi
Type I IFN signaling blockade by a PASylated antagonist during chronic SIV infection suppresses specific inflammatory pathways but does not alter T cell activation or virus replication
PLoS Pathogens 2018cited by 43position: middledoi
<i>Mamu-B*17</i> <sup>+</sup> Rhesus Macaques Vaccinated with <i>env</i> , <i>vif</i> , and <i>nef</i> Manifest Early Control of SIVmac239 Replication
Journal of Virology 2018cited by 13position: middledoi
Defining total-body AIDS-virus burden with implications for curative strategies
Nature Medicine 2017cited by 414position: middledoi
Early antibody therapy can induce long-lasting immunity to SHIV
Nature 2017cited by 315position: middledoi
A single gp120 residue can affect HIV-1 tropism in macaques
PLoS Pathogens 2017cited by 30position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Brandon F. Keele · Center for Cancer Research12 papers (2013–2025) · 12 papers (2012–2016)Ronald C. Desrosiers · University of Miami10 papers (2015–2025)Eva G. Rakasz · Wisconsin Department of Health Services9 papers (2012–2024)Jacob D. Estes · MIT University9 papers (2012–2017)Guido Silvestri · International AIDS Vaccine Initiative8 papers (2012–2021) · 7 papers (2016–2019)David I. Watkins · George Washington University7 papers (2012–2024)Mirko Paiardini · Emory Healthcare6 papers (2012–2021)Maurício A. Martins · Scripps Research Institute6 papers (2012–2025)Steven E. Bosinger · Emory University5 papers (2013–2021)Sebastian Fuchs · University of Miami5 papers (2015–2025)José M. Martinez-Navío · University of Miami5 papers (2015–2025)Guangping Gao · Institute for Biomedical Research and Innovation5 papers (2015–2025) · 4 papers (2012–2016)Kirk A. Easley · Emory University4 papers (2015–2021) · 4 papers (2013–2018)David B. Allison · University of Alabama at Birmingham4 papers (2012–2015)Ann Chahroudi · Emory University4 papers (2015–2021) · 4 papers (2014–2024)
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